— Permanent position – based in Lyon
I - MISSIONS
The Technological Unit “Management and Data analysis” has to develop technologies and solutions allowing to collect, follow, analyze, visualize and exploit the data generated by the experimental devices of the others BIOASTER units: genomics, transcriptomics, proteomics, metabolomics, cytometry, imaging, etc.
BIOASTER has also other sources of information from preclinical or clinical studies.
The candidate will :
Develop the processes allowing a global analysis of the genomics, transcriptomics, proteomics, metabolomics, cytometry results, in association with the appropriate units,
Contribute to the automation and the integration of these processes at the heart of the Scientific Information system and the bio-computing platforms of BIOASTER,
Propose a methodological jump concerning the statistical analysis of high dimensional data – from multi-omics, phenotypic and/or clinical origin - to bring strong and innovative answers to translational sciences issues of the TRI , e.g the identification of biomarkers or the characterization of mechanisms of action, by taking more particularly into account the duality and the complexity of host-pathogen systems.
II - ACTIVITIES
In collaboration with the bioinformatics community of BIOASTER, realize the state of the art and estimate the methods regarding integrative analyses of genomic, transcriptomic, proteomic and metabolomic data, as well as to contribute to their developments,
In association with the bioinformatics community of BIOASTER, participate in the evaluation of the statistical methods for the transformation, the standardization and the integration of the data (omics, phenotypic or clinical),
Contribute to the analysis of data generated in collaborative projects led by BIOASTER with industrial, academic or SME partners,
Participate in the evolution of the data management, the data analysis and the data visualization operated by the bioinformatics platform, or other services managed by the team.