Computational Biology and Biomarker Research in Heart Diseases

PROOF Centre of Excellence / University of British Columbia
Job Location
Vancouver, BC
Commensurate with experience
Job Description

ONE post-doctoral position (one-year term and extendable for another year with satisfactory progress) is available immediately for a highly motivated recent PhD or MD/PhD graduate to join collaborative research teams at the Centre of Excellence for the Prevention of Organ Failure (PROOF Centre) and UBC Center for Heart Lung Innovation. The position will be focused on computational biology and the characterization of biomarkers in chronic heart disease.

The Heart Failure and Heart Transplantation research fellow will work under the supervision of Bruce McManus, MD, PhD, a professor in the Department of Pathology at the University of British Columbia and CEO of PROOF Centre, and Raymond Ng, PhD, a professor in the Department of Computer Science at the University of British Columbia and Chief Informatics Officer at the PROOF Centre. The research will involve comparing genomic and proteomic data from tissue and blood samples to enhance the biological understanding, diagnosis, prognosis or monitoring of heart failure and heart transplant rejection.

The latest computational biology approaches will be used to identify specific biological pathways underlying heart failure or rejection, thereby improving our understanding of the mechanisms and biomarkers involved in these conditions. The position will be an exceptional opportunity for a highly talented and ambitious young investigator with a strong background in computational biology, plus proven experience with high-throughput data analyses. The successful applicant will be expected to make major discoveries related to cardiac disease and inflammatory/immune conditions.


Interested individuals with a recent PhD or MD/PhD, strong publication records and excellent academic credentials are encouraged to apply. Prior expertise in computational biology approaches, including data mining and systems science, is a requirement. Prior experience in immunology, cardiac biology, or functional genomics is a bonus. UBC hires on the basis of merit and is committed to employment equity. We encourage all qualified persons to apply. However, Canadians and permanent residents of Canada will be given priority.

How to Apply

Please submit a cover letter, curriculum vitae, transcripts from formal post-secondary school education, and the names and full contact information for three professional references.

The cover letter should include a description of your previous research experience and long-term career goals. Send electronic applications by February 12 to: [email protected]

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