Computational biologist/Bioinformatician/Biostatistician

4D pharma Cork Ltd
Job Location
Commensurate with experience.
Job Description

We are seeking a highly motivated and experienced computational biologist/bioinformatician/biostatician to join the 4D pharma Cork bioinformatics team to develop and implement computational models and apply machine learning algorithms and statistical methods to patient data. The goal is to stratify patients according to their clinical and microbiome data and to predict the likelihood of their response to a therapeutic agent. 

Key Areas of Responsibility

  • To stratify patients according to their clinical and microbiome data and to predict the likelihood of their response to a therapeutic agent. 

  • To mine, integrate and visualize multiple -omics datasets and clinical metadata to make correlations, predict gene function and identify biomarkers of disease.

  • Liaise with project team including clinical and research staff, to ensure timely processing of data to advance the research programme.

  • Maintain and manage all data in a safe and secure manner at all times.

  • A PhD in machine learning/bioinformatics/biostatistics, or an MSc with ideally at least 3 years’ relevant experience.

  • A proven track record in the application of scientific computing, machine learning or statistical methodologies preferably dealing with next-gen sequencing datasets.

  • Significant experience with the analysis of high-throughput datasets and integrative analysis of diverse omics datasets from different platforms.

  • Track record of independent critical thinking and scientific achievement evidenced by excellent publication record.

  • Experience with two or more computational/statistical languages such as but not limited to R/bioconductor, Java, Perl, python, stata and Bash shell-scripting experience (Unix).

  • The candidate should be knowledgeable, highly motivated, creative, and collaborative.

  • Excellent verbal and written communication skills. that Garda vetting and international police clearance check may form part of the selection process.

How to Apply

Please send all applications to: Candidates should submit a curriculum vitae including contact details for 2 referees along with a covering letter to arrive no later than Friday May 12th. For any queries or further information on the post please contact Prof Paul O’ Toole ( or Dr Ian Jeffery (  

About Our Organization

4D pharma Cork Ltd is a spin-out from the APC Microbiome Institute founded in February 2016 by Professor’s Fergus Shanahan and Paul O’Toole. The focus of the company is to investigate how variations in the composition of bacterial communities in the gut can aid the diagnosis and treatment of disease. Recent advances in the field have highlighted the importance of the gut microbiome, not only for the development of safe and efficacious new therapeutics, but also for the discovery of novel personalised diagnostic tools. 4D pharma Cork Ltd is a subsidiary of 4D pharma plc (, a UK pharmaceutical company focusing on the development of live biotherapeutics, a novel and emerging class of drugs. While the initial focus of the spin-out company is on diagnosis and patient stratification for Irritable Bowel Syndrome (IBS), the long-term objective is to build a diagnostic platform across multiple disease areas, mirroring 4D’s proprietary MicroRx platform for the discovery of live biotherapeutics.

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