Computational biologist/Bioinformatician/Biostatistician

4D Pharma Cork Ltd
Job Location
Commensurate with experience
Job Description

This is a full-time position to develop and implement computational models and apply machine learning algorithms and statistical methods to patient data. The goal is to stratify patients according to their clinical and microbiome data and to predict the likelihood of their response to a therapeutic agent.  The successful candidate will apply their extensive experience in mining, integration and visualization of multiple -omics data sets and clinical metadata. S/he must be capable of working independently as well as part of a team to develop and apply computational solutions to biological questions.


•             A PhD in machine learning/bioinformatics/biostatistics, or an MSc with at least 3 years’ relevant experience.

•             A proven track record in the application of scientific computing, machine learning or statistical methodologies preferably dealing with next-gen sequencing datasets.

•             Significant experience with the analysis of high-throughput datasets and integrative analysis of diverse omics datasets from different platforms.

•             Track record of independent critical thinking and scientific achievement evidenced by excellent publication record.

•             Experience with two or more computational/statistical languages such as but not limited to R/bioconductor, Java, Perl, python, stata and Bash shell-scripting experience (Unix).

•             The candidate should be knowledgeable, highly motivated, creative, and collaborative.

•             Excellent verbal and written communication skills.

How to Apply

Candidates should submit a curriculum vitae along with a covering letter  to the following email address: to arrive no later than Friday November 18th. For any queries or further information on the post please contact Prof Paul O’ Toole ( or Dr Ian Jeffery (

About Our Organization

4D pharma Cork Ltd is a spin-out from the APC Microbiome Institute founded in February 2016 by Professors Fergus Shanahan and Paul O’Toole. The focus of the company is to investigate how the composition of bacterial communities in the gut can aid the diagnosis and treatment of disease. Recent advances in the field have highlighted the importance of the gut microbiome, not only for the development of safe and efficacious new therapeutics, but also in the discovery of novel personalised diagnostic tools. 4D pharma Cork Ltd was formerly known as Tucana Health Ltd. before recently being acquired by 4D pharma plc, a UK pharmaceutical company focusing on the development of live biotherapeutics, a novel and emerging class of drugs. While the initial focus of the spin-out company will be on diagnosis and patient stratification for Irritable Bowel Syndrome (IBS), the long term objective is to build a diagnostic platform across multiple disease areas, mirroring the programmes developed by 4D’s proprietary platform, MicroRx for the discovery of novel live biotherapeutics. We are now seeking a highly motivated and experienced computational biologist/bioinformatician/biostatician to join the 4D pharma Cork bioinformatics team.

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