Computational Biologist - Genome Sequencing Center

HudsonAlpha Insitute for Biotechnology
Job Location
601 Genome Way
Huntsville, AL 35806

HudsonAlpha offers a competititve benefits package.

Job Description


The Institute houses a variety of quasi-independent laboratories, each with its own unique research objective(s). Each laboratory develops its particular protocols and manages materials and equipment. Laboratories operate under the direction of a Principal Investigator or team of Investigators and assignments are made within the research team based on areas of expertise and overall objectives of the lab.  The HudsonAlpha Genome Sequencing Center ( is a not-for-profit research group focusing on the generation of high quality plant and fungal genomic resources for the scientific community. It specializes in eukaryotic whole genome sequence, assembly, and analysis together with improvement or finishing of complex eukaryotic genomes.


A successful Computational Biologist should be able to address complex scientific questions using next generation sequencing technologies by applying a combination of computational and biological expertise.  The candidate should be able to assist in designing experiments that address the problem at hand and then take the resultant data and design/apply computational methods that specifically address problems related to functional plant genomics.


  • Support of scientific research using technical knowledge of software, software development, networking, and/or hardware in a complex computing environment. .
  • Perform complex data analysis related to specialized research methodologies and results as assigned by the Principle Investigator.
  • Develop and/or modify software to support new and ongoing research projects.  





Education and Experience:

  • Bachelor degree in computational biology, biostatistics, or related quantitative field; Master's degree a plus
  • Knowledge of current bioinformatics approaches and databases
  • Ability to apply mathematical modeling to biological data
  • Excellent programming skills
  • Strong understanding of statistics and quantitative data analysis
  • Excellent communication skills, demonstrating ability to understand objectives of research team and write explanations for research papers
  • Proficient with MS Office

Required Skills:

  • Subject matter expert in multiple areas of computing technology, and specific knowledge of molecular biology and genetics
  • Knowledgeable in computational biology, biostatistics, bioinformatics.
  • Comfortable constructing bioinformatics pipelines that interface with internal and external resources.
  • Fluency with UNIX, and able to function in a cluster computing environment.
  • Strong statistical background.


The physical requirements and environmental conditions of this position consist primarily of:

  • Continuous mental and visual attention, requiring sustained attention and observation
  • Ability to work at a computer monitor for most of the work day



About Our Organization


HudsonAlpha Institute for Biotechnology is a non-profit facility with the mission to use biotechnology and basic biological research to make important discoveries, improve human health, stimulate economic development and inspire young people to seek careers in science. Located in Cummings Research Park in Huntsville, Alabama, one of the world's leading science and technology business parks, the four-story, 270,000 square foot building contains state-of-the-art laboratories for biological research and development in the areas of genomics, genetics and personalized medicine.

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