Our goal is to make the human genome practically useful for life-altering decisions. Our clinical assays screen tens of thousands of patient samples per month for autosomal recessive genetic disease (like Cystic Fibrosis and Tay-Sachs disease), Down’s syndrome, and inherited risk of developing various forms of cancer (like BRCA and Lynch Syndrome). Our patients are people who are interested in maximizing their own health and the health of their children. Our assays are performed on over 5% of pregnancies in the United States. As a Computational Biologist at Counsyl, your role will be to invent a new generation of clinical molecular diagnostic tests. As a member of a tight interdisciplinary team, you’ll work closely with molecular biologists, geneticists, and software engineers to invent and construct novel assays based on Next Generation Sequencing. Contributions include developing statistical analysis methods for new DNA sequencing assays, extracting robust signals from noisy experimental data, working with molecular biologists to refine sequencing protocols, and sharing your methods in the form of simple re-usable software. Must thrive in a professional atmosphere, where interdisciplinary teams are central to project success.
What you'll do
- Work closely with molecular biologists, geneticists, and software engineers to research and prototype new clinical molecular diagnostic assays.
- Characterize data resulting from novel molecular assays and guide protocol development from a statistical perspective.
- Originate new ideas for genetic testing, and lead interdisciplinary teams in exploring those ideas via experimentation.
- Develop working prototypes that can be translated into the high-volume production lab.
- Work with legal staff to secure intellectual property rights for your inventions.