Computational Biologist (210155)

Organization
The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF)
Job Location
Bethesda, MD 20814
Job Description

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) is seeking a Computational Biologist to join the CHIRP (https://www.usuhs.edu/chirp) program in the Bioinformatics Core.  The Computational Biologist will design and execute computational genomics and statistical analysis, e.g. mutation discovery and trait association in large DNA WGS cohorts and genomewide RNA expression analysis.   This is an exciting opportunity to be a lead scientist for a new whole genome sequencing center.  Salary is commensurate with experience.

The Collaborative Health Initiative Research Program (CHIRP) is a precision medicine collaborative research program between the National Institutes of Health and the Department of Defense. CHIRP is based at Uniformed Services University, on the campus shared with the Walter Reed National Military Medical Center.  The Henry Jackson Foundation (HJF) provides scientific, technical and programmatic support services to CHIRP.

Responsibilities:

  1. Evaluates, analyzes, and customizes next generation sequence analysis protocols, e.g. Hiseq Analysis Software, GATK, open source software, for a variety of sequencing applications.
  2. Develops new WGS, RNA-seq, Exome seq, genome analysis pipelines and procedures.
  3. Performs genome wide trait association analyses using tools such as Plink/seq, glm.
  4. Conducts data‐driven and hypothesis-directed genomics research.
  5. Provides analytical support to CHIRP investigators.
  6. Assists with the report of experimental results for publication in technical and peer-reviewed journals.  Contributes and edits data, text and figures in program publications.
  7. Provides collaborative assistance to USU personnel that require the incumbent's expertise.
  8. May supervise junior informatics staff.


Required Knowledge, Skills, and Abilities:  Research experience in computational genomics or biostatistics demonstrated through publications; programming ability in (R or other statistical language), scripting language (Perl, Python, or comparable), and (C/C++, Java or comparable language); experience with next-generation sequencing analysis i.e. alignment, quality assessment, variant detection, statistical inference; preferred experience with trait association analysis such as Plink, glm;  experience with pipeline development and implementation on compute clusters; experience with power calculations and study design; demonstrated ability to work effectively as part of a team in a deadline-driven environment; good communication and analytical skills.

Minimum Education/Training Requirements:  Ph.D. in Computational Biology, Bioinformatics, Biostatistics, Computer Science or related discipline.  Master’s degree with post degree work experience also considered.

Minimum Experience:  5 years related experience, of which degree program can be contribute towards.

Physical Capabilities:  Extended periods of sitting and working at a computer.

Work Environment:  Office or laboratory environment.

Please apply online at careers.hjf.org click "Advanced Search" and enter job number 210155 in the Job Opening ID box.

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) is an equal opportunity and affirmative action employer.  All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status or other status protected by law.

How to Apply

Please apply online at careers.hjf.org click "Advanced Search" and enter job number 210155 in the Job Opening ID box.

About Our Organization

The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc. (HJF) is a global organization dedicated to advancing military medical research. We serve military, medical, academic and government clients by administering, managing and supporting preeminent scientific programs that benefit members of the armed forces and civilians alike.

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