Computational Biologist

Freenome Holdings Inc
Job Location
201 Gateway Boulevard
South San Francisco, CA 94080
Job Description

As a computational biologist at Freenome, you will be an integral part of our R&D team, working in collaboration with machine learning specialists to develop the core analysis technology driving Freenome’s mission of early detection and intervention in human disease. You will also work closely with our molecular biologists to evaluate new laboratory methods that can drive improvements in end-to-end assay performance.



    • PhD (or equivalent research experience) in computational biology, bioinformatics, cancer biology, genomics, or a related field
    • Extensive experience working with next-generation sequencing data. You’ve analyzed raw reads to test scientific questions
    • Proficiency in at least one general-purpose programming language: Python, Java, C++, etc
    • Proficiency in a scientific data processing ecosystem: R, Python/Numpy, etc
    • Basic knowledge of statistics: significance testing (and the hazards therein), Bayes’ theorem, properties of basic probability distributions used in computational biology
    • Skilled at clearly communicating scientific results with a team and working collaboratively towards next steps

 Above The Average

    • 3+ years postdoctoral research in industry or academia and demonstrated success in leading research and development projects
    • Expertise in oncology, immunology, developmental biology, or similar applied fields
    • Experience working with NGS data beyond diploid germline DNA-seq: RNA-seq, single-cell sequencing, metagenomics, epigenomics, etc
    • Experience working with other digital biological data: mass spec, images, EHR/EMR, etc
    • Bench experience: you’ve analyzed data you generated yourself
    • Applied experience in machine learning: cross-validation, parametric and nonparametric  regression, hierarchical modeling, ensemble learning, neural networks, and graphical models
    • Experience with software engineering best practices: code quality, testing, performance optimization, development of research tools infrastructure
About Our Organization

Freenome’s CultureOur culture is simple. We value Empathy, Trust and Integrity. We feel from the perspectives of each other, patients and the communities we serve. We give each other the benefit of the doubt and believe we’re all working as a team towards our goals. We conduct ourselves with integrity, empowering others to grow in a collaborative environment. Freenome explicitly  prohibits any form of workplace harassment based on race, color, religion, gender, sexual orientation, gender identity or expression, national origin, age, genetic information, disability, or veteran status. 

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