Clinical Variant Curator

Organization
Memorial Sloan Kettering Cancer Center
Job Location
New York, NY 10065
Salary
TBD
Benefits

Memorial Sloan Kettering’s (MSK) benefits program acknowledges the care that our employees put into their jobs every day. The program provides benefits, tools, resources and services to help employees at work, and in their lives outside of work. MSK is committed to providing a comprehensive benefits package - our benefits are all about Making Life Better. 

Job Description

The Clinical Variant Curator is a position that assists the clinical and developmental operations of the Diagnostic Molecular Genetics Laboratory to accurately identify and precisely classify variants/mutations detected through standard clinical
genetic testing.

In addition to our existing mutation detection platforms, next-generation sequencing applications for germline targets will generate a large amount of variants which requires a focus towards curation, interpretation and classification. Using
information from existing databases, and more importantly, from literature, this specialist will help identify and assess genetic variant(s) in an individual as pathogenic or not. Such clinical interpretation is a critical component for the reporting of molecular genetic testing results. 

Duties include assisting Laboratory Director in overseeing the test development and clinical testing pipelines in conjunction with the interpretation and classification of genetic variants identified. Cross-departmental communications with our Clinical Genetics Services (CGS) for clinical sign out is critical. Candidates should have a strong background in variant assessment computational tools and germline genetic knowledge. Additional opportunities in translational clinical developmental activities will also be offered.

Requirements

Minimum Qualifications:

A Master’s Degree and a minimum of 2-3 years of sequencing data interpretation experience is required. Laboratory and/or clinical experience in cancer genetics required. A strong background in Human Genetics is essential. Applicants to this position should have an in-depth understanding of the biology, molecular mechanisms and functional studies of cancer susceptibility genes. The ability to critically read, understand, and interpret data from scientific publications on a daily basis is required. This position requires cross-disciplinary and strong analytical skills as well as broad experience using computational methods, databases, software and hardware.

Preferred Qualifications:

A PhD in Life Sciences (Molecular Biology/Genetics) and familiarity with Germline databases, Sanger Sequencing, Pyrosequencing, and Next-generation sequencing (NGS) experience preferred. 

 

About Our Organization

For over 130 years, the people of Memorial Sloan Kettering have been relentless pioneers in our single-minded focus on the prevention and cure of cancer. We are known for intensely innovative research that never stops, as well as for  thoughtful,compassionate, and responsive patient care that treats the individual first.

Memorial Sloan Kettering is the world's oldest and largest private institution devoted to the prevention, treatment and cure of cancer. We have dedicated more than a century to patient care and innovative research, and are recognized as one of only 41 National Cancer Institute-designated Comprehensive Cancer Centers.

When you work within our organization, you will be part of a team with a purpose. You will be encouraged to learn and grow through responsibility and collaboration. Most important, you will contribute to the fulfillment of our mission: the progressive control and cure of cancer through programs of patient care, research and education.

MSKCC is an equal opportunity and affirmative action employer committed to diversity and inclusion in all aspects of recruiting and employment. All qualified individuals are encouraged to apply and will receive consideration without regard to race, color, gender, gender identity or expression, sexual orientation, national origin, age, religion, creed, disability, veteran status or any other factor which cannot lawfully be used as a basis for an employment decision. 

 

Federal law requires employers to provide reasonable accommodation to qualified individuals with disabilities. Please tell us if you require a reasonable accommodation to apply for a job or to perform your job. Examples of reasonable accommodation include making a change to the application process or work procedures, providing documents in an alternate format, using a sign language interpreter, or using specialized equipment.

 

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