Clinical Bioinformatician

Job Location
St. Louis, MO
Job Description

• Work with a cross-functional team of scientists, software developers, engineers and medical professionals to develop a novel Clinical NGS informatics platform.
• Build and support cutting-edge pipelines for the analysis and interpretation of clinical NGS data from variant calling, classification, and interpretation.
• Analyze clinical assay validation data sets to determine optimal computational pipelines.
• Implement cutting-edge computational methods and develop novel solutions through software enhancements that touch all aspects of NGS data analysis.
• Ensure that software adheres to regulatory requirements required of clinical diagnostic laboratories.
• Maintain expertise in the science and application of genomic technologies.


• Masters degree and 2+ years or BS degree and 4+ years experience (or equivalent combination of education and experience); preferred degree in Bioinformatics, Computational Biology, Biostatistics, or other relevant discipline.
• 2+ years of experience in one or more of the following areas: Next Generation Sequence analysis; Genome Annotation.
• Demonstrated fluency in UNIX/Linux and high performance computing environments
• Demonstrated programming/scripting ability in languages such as Perl/Python/Java/C++ and familiarity with principles of object oriented programing
• Experience in algorithm generation and/or computational methods implementation
• Familiarity with statistical/mathematical packages such as R/MATLAB

About Our Organization

PierianDx enables clinical labs to deliver patient-specific diagnosis and treatments based on an individual’s DNA. In active use since 2011 by Washington University in St. Louis, PierianDx’s proprietary Clinical Genomicist Workstation software, knowledgebases, IT backbone and workflow management tools provide an end-to-end solution for managing clinical next-generation sequencing processes. For more information, please visit or @PierianDx on Twitter.

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