Chief Medical Officer

Organization
3D Signatures Inc.
Job Location
Toronto, Ontario, Canada
ON
Canada
Salary
TBD
Benefits

3D Signatures Offers a comprehensive benefits package and performance based bonus program

Job Description

 

The company is searching for a Chief Medical Officer to ensure its continued success, and to assist the company in transforming its 3D Telomere Technology into a disruptive platform of diagnostic/prognostic tests that will become commercially attractive to clinically laboratory partners and diagnostic companies. 3DS is at the late stage of completing its validation work on the company’s proof of principle Hodgkin’s lymphoma test and it expects to identify a commercial partner in 2017. In addition, the company intends to evaluate additional clinical development opportunities for its technology in prostate cancer, multiple myeloma, lung cancer, Alzheimer’s disease and breast cancer to name a few. The CMO will be based in Toronto, Canada, and report to the CEO, also in Toronto. She/he will have responsibility for the clinical strategy, implementation of the clinical development and operations plan, as well as oversight of the daily operation of test/assay development projects. She/he will collaborate with key internal stakeholders such as the CBO, CFO, VP Clinical, Director Clinical Operations and external stakeholders including CROs, key opinion leaders, investors, analysts and the company’s Clinical and Scientific Advisory Board (CSAB), including the CSAB Chair and co-founder of 3DS. The Chief Medical Officer will join the company’s senior leadership team. 

Requirements

We seek candidates with the following qualifications:

 

  • MD with seven to ten years of industry in related fields, or PhD with direct industry experience.
  • Must demonstrate knowledge of the clinical development process for diagnostics/prognostics and have direct clinical research and managerial experience. Managing trials in cancer diagnostics/prognostics would be an asset.
  • Experience in developing clinical tests, including laboratory developed tests (LDTs) and in-vitro diagnostic devices (IVDs).
  • Knowledge of clinical trial management and data management.
  • A detailed understanding of CAP/CLIA/ISO/GMP clinical laboratory standards and requirements for licensing. 
  • A detailed understanding of oncology, and the relevance of clinical endpoints and how diagnostic/prognostic tests can aid in personalized medicine.
  • Documented knowledge of molecular imaging required (fluorescent in situ hybridizations, 3D imaging vs. 2D imaging as a minimum). Documented knowledge of quantitative imaging (fluorescent microscopy) is an asset.
  • Prior experience in clinical study design, implementation of protocols, review/interpretation of data is required. This could be obtained through prior work in the diagnostic or pharmaceutical industry.
  • Knowledge of regulatory paths and experience in seeking IVD approvals through FDA .
  • Excellent oral and written communication skills, as well as interpersonal skills.

Major Duties and Responsibilities:

  • Provide strategic medical input into clinical development strategies for the company’s diagnostic/prognostic tests.
  • Design, direct and oversee the implementation of all clinical projects.
  • Ensure that the overall scientific and medical content of all clinical programs is sound and aligned with the company’s goals and actionable commercial outcomes.
  • Prepare clinical development plans with detailed timelines and institute properly approved clinical protocols.
  • Design scientifically rigorous and cost-effective clinical development programs for the desired diagnostic/prognostics tests. Present and defend protocols.
  • Implement clinical R&D programs, policies, SOPs and related directives.
  • Monitor study progress, leading the analyses and data evaluation process for progress reporting and presentations to senior management, CSAB and Board members.
  • Prepare or direct the preparation of various official and regulatory documents for Regulatory and other agencies or partners.
  • Manage design and application of medical ethics.
  • Recruit and manage multidisciplinary professionals and clinical scientists as well as support career and project advancement.
  • Review potential out-licensing opportunities. Support any needed due diligence and prepare/present medically sound strategy and plans associated with advanced opportunities.
How to Apply

Do you have the skills, experience and qualities we seek and want to advance your career with a rapidly growing company? If so, please share your resume/CV with us and include your preferred daytime contact information.

 

For inquiries or to submit an application please email [email protected]

About Our Organization

3D Signatures (3DS) (TSXV:DXD; OTCQB:TDSGF; FSE:3D0) is a personalized medicine company with a proprietary software platform based on the three-dimensional analysis of chromosomal signatures. The technology is well developed and supported by 22 clinical studies on over 2,000 patients across 13 different cancers and Alzheimer’s disease. Depending on the desired application, this platform technology can measure the stage of disease, rate of progression of disease, drug efficacy, and drug toxicity. The technology is designed to predict the course of disease and to personalize treatment for the individual patient. For more information, visit the Company’s new website at http://www.3dsignatures.com.

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