Career Development Fellowship in Functional Genomics

University of Leeds
Job Location
Section of Genetics
Wellcome Trust Building St James's University Hospital
United Kingdom
£31,342 to £37,394

The University of Leeds is committed to providing equal opportunities for all and offers a range of family friendly policies ( The University is a charter member of Athena SWAN and holds the Bronze award. The School of Medicine gained the Bronze award in 2013.  We are committed to being an inclusive medical school that values all staff, and we are happy to consider job share applications and requests for flexible working arrangements from our employees.

Job Description

  We are looking for talented, highly motivated post-doctoral researchers to join the Institute to establish independent and substantial research portfolios in the structural and functional characterisation of genes and mutations with medical significance. Main areas of clinical research are in neurologic, neuromuscular and developmental diseases in children but we welcome applications from individuals with interests in other areas that could contribute to the research of the Section.

The Career Development Fellowship is funded, through investment from the School of Medicine, for a period of three years to allow you to develop your own academic research profile, including submission of grant and fellowship applications and publications in high quality journals.  It is expected that research activities undertaken will enable you to ultimately secure a personal fellowship.

You will progress through a detailed probation development plan and will also receive focused support and mentorship to aid you in achieving these objectives and realising your potential.
There is a well-developed pipeline for the identification of novel disease genes, with access to state of the art Next Generation sequencing facilities, Bioinformatics, and Single Cell Genomics. You will have direct access to unique clinical resources, as a result of the close working partnership between researchers in the section of genetics and colleagues at the Leeds Teaching Hospitals NHS Trust, and access to the wide range of facilities and the clinical material to develop your own research portfolio within the context of the Section’s activity.

You should have expertise in one or more general areas of functional genomics/bioinformatics, with the following given as examples:

• Whole Exome Sequencing
• Single-cell functional genomics methods such as transcriptome profiling
• Methods to analyse biochemical interactions between proteins and/or small molecules
• Methods to interrogate the effect of mutations on protein functions/interactions
• Developing your own bioinformatics tools and/or bespoke programs

You will join an enthusiastic team of researchers and will be expected to collaborate with research teams throughout the institute, the School of Medicine and the wider university. You will contribute to the scientific strategy and teaching commitments of the institute, including our new BSc courses in Molecular Medicine and Human Genetics.

Candidates must be enthusiastic, highly motivated and demonstrate a high level of relevant laboratory experience and technical competence. You must have a strong track record in successful research and a developing publication record in high impact peer reviewed journals. You will possess the ability to manage your time effectively and work under pressure, exhibiting effective interpersonal, communication, and team-working skills. Adaptability to and enthusiasm for new technologies is desirable.

Full details are available here:

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This is a post for an experienced post doc, with at least five years post doc experience. The objective is to be able to dvelop your own independent research portfolio, acheive grant income and generate high quality publications. The aim is that by the end of the fellowhip the post holder will be in a position to apply for an independent Research Fellowship form one fo the major Research Charities. Therefore exprience in a range of molecular biology techniques and a strong publication record are required. More detailed requirements are given in the job description available at the URL above.

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