Biostatistician/Bioinformatician: Transcriptomics/Epigenetics in brain diseases

Organization
German Center for Neurodegenerative Diseases
Job Location
37077 Goettingen
Germany
Salary
according to institutional guidelines
Job Description

Positions for a Biostatistician and/or bioinformatitian is available immediately.

 

 

The group of  Prof. Dr. Andre Fischer group is located at the Department for Psychology and Psychotherapy at the University Medical Center in Göttingen and the German Center for Neurodegeneative diseases in Goettingen/Germany. The group works on epigenetic and transcriptional mechanisms in neurodegenerative and neuropsychiatric diseases (http://fischerlab.uni-goettingen.de/index.php) (http://www.dzne.de/standorte/goettingen/struktur.html)

 

The successful candidate will work within a team consisting of wet-lab researchers and bioinformaticians in a multidisciplinary environment spanning bioinformatics and neuroscience. The project will focus on the integrative analyses of various genome-wide datasets derived from massively parallel sequencing (ChIP-seq, bisulfite-seq, RNA-seq, small RNA-seq, etc. and phenotypic data). The current project has a particular focus on non-coding RNA and RNA splicing.

 

Thus, candidates should have a documented background in bioinformatics, computational biology and/or biostatistics. He or she will work in collaborative and dynamic environment, and have a proven track record of productivity. The salary will be established according to institutional guidelines. The position is initially limited to 3 years.

 

Applicants should send a letter of research interests, curriculum vitae, the names and contact details of two referees to [email protected]

 

The University Göttingen and the DZNE is an equal opportunity employer seeks to increase the number of female personnel in those areas where women are underrepresented and therefore explicitly encourages also women to apply.

 

Further readings

 

Fischer, A. Epigenetic Memory: The lamarckian brain, EMBO J. 2014 Epub ahead of print

 

Benito, E. et al.  Fischer, A. Reinstating transcriptome plasticity and memory function in models for cognitive decline, Journal of Clinical Investigation, in press

 

Stilling, et al.  Fischer, A. De-regulation of gene expression and alternative splicing affects distinct cellular pathways in the aging hippocampus. Frontiers in Cellular Neuroscience, 8:373. eCollection (2014).

 

Stilling, R.M et al. Fischer. A. K-lysine acetyltransferase 2a regulates a hippocampal gene-expression network linked to memory formation. EMBO J. (2014) 33, 17, 1912-1927

Peleg, S., et. Al. Fischer, A.   Altered histone H4 lysine 12 acetylation is associated with age-dependent memory impairment in mice. Science, 328; 753, 2010

 

 

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