Biostatistician – R&D Support Projects

Organization
ArcherDX
Job Location
2477 55th Street, Suite 202
Boulder, CO 80301
Job Description

This person’s main responsibility will be to analyze, design and interpret NGS experiments performed by molecular biologists. This person will have a strong understating of molecular biology. They will have a very strong ability to design experiments that give meaningful metrics from NGS data. A grasp of statistical significance, importance of replicates and ideally experience with "design of experiment" concepts, which are often times counter-intuitive but powerful and efficient in optimizing large numbers of experimental parameters. Software ability will be secondary, but this person should at least have a working knowledge of common scripting and statistical languages like python/bash/R/awk/sed/grep. They should have the ability to write simple scripts while leveraging 3rd party tools in order to support in analysis of the experiments that they help design.

  • Design and interpret experiments to improve existing, and generate new genotyping applications for a targeted sequencing assay
  • Work closely with molecular biologists in order to ensure meaningful statistical analysis can be performed on the resulting data
Requirements
  • Understanding general principals of experimental design (randomization, replication, blocking, orthogonality, etc).
  • Strong understand of molecular biology
  • Ability to leverage open source 3rd party tools in order to complete analysis
  • Write scripts in python/bash/R/awk/sed or any pertinent scripting languages or statistical packages

KEY TECHNOLOGIES OR ROLESDesign of Experiments, R, Python, NGS Statistics

EXPERIENCE

  • Understanding general principals of experimental design (randomization, replication, blocking, orthogonality, etc).
  • Strong understand of molecular biology
  • Ability to leverage open source 3rd party tools in order to complete analysis
  • Write scripts in python/bash/R/awk/sed or any pertinent scripting languages or statistical packages

EDUCATION

  • BS or better preferred.
About Our Organization

ArcherDX, the NGS applications company, is developing and commercializing a novel approach to target enrichment chemistry. Next-generation sequencing technology based on Anchored Multiplexed PCR (AMP™) generates a highly enriched library of gene targets of interest for downstream genomic sequencing. Complemented by proprietary software and readily accessible reports, our technology enables dramatic enhancement in mutation detection speed as well as complex mutation identification and discovery.

An analysis appearing in PeerJ finds that social media mentions of a paper may lead to increased citations.

NIH's Michael Lauer looks at the number of grants, their amount, and funding success rates at the agency for last year.

At Nature, Johns Hopkins' Gundula Bosch describes her graduate program that aims to get doctoral students thinking about the big picture.

Patricia Fara writes about childcare funding, and women in science and science history at NPR.