Bioinformatics Systems Analyst (Sequencing Technology) - 80318
The DOE Joint Genome Institute (JGI) in Walnut Creek, CA (a division of the Lawrence Berkeley National Lab) has an exciting opportunity available for a Bioinformatics Systems Analyst to perform large-scale data analysis and develop computational tools for R&D projects surrounding genome, transcriptome and chromatin characterization.
This role will evaluate the nature of biological challenges, design of molecular biological approaches and short read sequencing data, as well as thoroughly analyze DNA sequence data produced by next generation sequencing machines and various library types. Will develop and implement analysis pipelines, and provide technical and analytical data interpretation. Will also be responsible for improving existing data analysis tools and implement new tools for general use.
This position will have a significant role in defining biological significance of the data, will work with various JGI groups on data analysis projects and facilitate transfer of knowledge of technologies and applications to JGI staff. May also provide custom analysis support to external collaborators. Will report to the Sequencing Technology Group analysis work lead.
Sequence Analysis and Interpretation
• Perform quality analysis of sequence data and assist others in interpretation of analyzed data.
• Extract new biological insights and phenomenon from the analyzed results.
• Independently and proficiently utilize assembled genomes, various alignment tools, visualization tools, and other genome interrogation and analysis software.
• Be familiar with the different types of data and approaches for chromatin (epigenetic) interrogation, transcriptome characterization and genome assembly.
• Provide data quality feedback to wet-lab scientists and sequencing team members.
• Provide clear and concise professional reports on data analysis and results.
• Present technical and analytical status in weekly meetings.
• Contribute to publications on experimental data generated by the new sequencing approaches.
Bioinformatics Tool Adaptation and Improvement
• Adapt and improve bioinformatics tools to process sequencing data generated by various R&D library types and projects.
• Participate in the design and development of new tools for new R&D projects.
• Refine and improve existing analytical tools.
• Design and build new tools to analyze sequences of various research projects.
• Troubleshoot system and data analysis problems and provide feedback on areas of improvement for existing tools.
• Provide technical support to detect issues and improve library protocols.
• Provide high quality documentation for newly developed software and approaches.
In addition to the above, the following are responsibilities for the higher analyst level:
• May provide functional and technical guidance to others, including assisting co-workers in problem resolution.