Bioinformatics Scientist, Exploratory Bioinformatics

Genomic Health
Job Location
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Redwood City, CA 94063
Job Description


Genomic Health is seeking a highly talented and motivated Bioinformatics Scientist with cancer biomarker experience to develop products that help cancer patients make better informed treatment decisions. As a key member of the R&D team this individual will collaborate with other Bioinformatics Scientists, Laboratory scientists, Biostatistics, Data Management, and IT to design and implement NGS solutions in Liquid Biopsy program. A strong candidate will have a track record of successfully designing and implementing data analysis methods using next generation sequencing in a multidisciplinary team environment.


  • Design, implement, test, and deploy scalable bioinformatics data analysis methods and prototypes for cancer biomarker discovery and development, including genomic aberration, expression profiling and annotation
  • Evaluate, integrate, modify and tune open source and commercial utilities to fit research and product goals
  • Integrate multiple genomic features to optimize the performance of diagnostic products
  • Represent the bioinformatics function in project teams. Present at internal meetings.
  • BS/MS/Ph.D. in Bioinformatics, Computer Science, Statistics, Biological Science or a related technical field.
  • 3 years of experience designing and developing next generation sequence analysis methods.
  • Extensive experience with NGS bioinformatics applications, such as mapping algorithms, de novo assemblers, variant callers and annotation tools.
  • Excellent understandings of biostatistics with experience in both parametric and non-parametric analysis.
  • Strong coding skills in Python, PERL, R in a distributed Linux/Unix/Cloud environment. Familiar with Sun Grid Engine and batch job managing.
  • A strong communicator who effectively adjusts to technical and non-technical audiences.
  • Able to prioritize and deliver results with a high emphasis on quality, technical rigor, and attention to detail.
  • Able to integrate feedback in a professional manner and thrives in multidisciplinary teams with members with highly diverse backgrounds.
  • Experience commercializing or transferring bioinformatics pipelines to a production environment.



  • Experience with bioinformatics methods development to optimize the sensitivity of somatic mutation detection
  • Prior R&D exposure in a clinical diagnostics, pharma, or genome sequencing center setting.
  • Experience developing products in a regulated environment





  • Travel Requirements:
  • Standing or sitting for long periods of time may be necessary




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How to Apply

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