Bioinformatics Scientist, Cancer (Interpretation)

Organization
New York Genome Center
Job Location
101 Ave of the Americas
7th Floor
New York, NY 10013
Job Description

The New York Genome Center is looking for a highly motivated, results-driven individual to join the computational biology and genome analysis group within the informatics division. As a Bioinformatics Scientist, Cancer interpretation, you will be responsible for the analysis and interpretation of results from the Cancer genomics pipelines (somatic SNV and SV, integrated with RNA-Seq, epigenomics or other sequencing experiments applied to oncology). The job requires familiarity with all parts of the process from sequencing to calling and understanding somatic variation, as well as a deep knowledge of oncology, cancer pathways and an ability to connect genomics to biological and clinical expertise, through literature, knowledgebase and personal experience. We are seeking an individual who is passionate about understanding and modeling human genetic variation and how it can be used to generate clinically actionable results. Publication of developed methods and scientific findings is encouraged.

Job duties will include, but are not limited to:

  • Develop, apply and support innovative approaches for data analysis, modeling and prediction;
  • Implement methods for somatic variant prioritization, annotation and interpretation;
  • Plan, organize and support external collaborative initiatives;
  • Assist, collaborate, and consult with internal/external researchers on analyses of NGS data.

 

Requirements
  • PhD. in biology, bioinformatics, computational biology, genetics, computer science or similar;
  • Proficiency in utilizing data from public resources such as TCGA or COSMIC as part of data analysis or methods development. Participation in TCGA, COSMIC, etc. projects is a big plus;
  • Experience in cancer genomics, as demonstrated by publications in high impact journals;
  • Experience with the standard suite of bioinformatics tools (aligners, callers, etc.);
  • Experience with pathway / network analysis and visualization tools (Ingenuity, Cytoscape, etc)
  • Experience in R/Matlab, and scripting languages such as Python;
  • Experience working in Linux and running tasks in a cluster environment (e.g. SGE);
About Our Organization

The New York Genome Center is looking for a highly motivated individual to join our computational biology group. As Bioinformatics Scientist, Cancer you will be responsible for the analysis and interpretation of genomic data in oncology, a major area of interest at the NYGC. The job requires innovative problem solving in all parts of the process from sequencing to calling and understanding somatic variation, to biological interpretation, multimodal data integration and analysis of personalized treatment options. Collaboration with other members of the computational biology team as well as external collaborators and customers is paramount. Publication of developed methods and scientific findings is encouraged.

 

The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

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