Bioinformatics Scientist, Cancer Genomics

Organization
New York Genome Center
Job Location
101 Avenue of the Americas
New York, NY 10013
Job Description

The New York Genome Center is looking for a highly motivated individual to join our computational biology group. As Bioinformatics Scientist, you will be responsible for handling of custom analysis and reporting for NYGC staff and collaborators. You will also share technical responsibility for the maintenance, benchmarking, and continuous improvement of our cancer genome analysis pipelines. You will collaborate with analysts and programmers performing development and analysis in this area. You should have significant experience in cancer genomics, including familiarity with commonly used algorithms for alignment, variant calling, and structural variant calling. Expertise in one or more common disease areas would be ideal. Collaboration with other members of the computational biology team as well as external collaborators and customers is paramount. Examples of recent projects involve tumor evolution, tumor heterogeneity, liquid biopsy, and prediction of personalized treatments (such as targeted therapies or immunotherapy). Publication of developed methods and scientific findings is encouraged.

Job duties will include, but may not be limited to:
- Contribute to setup, management and maintenance of next generation sequencing (NGS) data analysis pipelines;
- Analyze sequencing data using the established pipeline(s);
- Stay current on innovations in DNA sequencing analysis;
- Develop and implement innovative computational approaches for the analysis of large sequence datasets from NGS technologies;
- Collaborate and consult with external and internal researchers on the analyses of NGS data;
- Interpret and present the results of the computational and statistical analyses to collaborators and coworkers;
- Work with the software engineering team to ensure pipeline upgrades and new pipelines are properly implemented in our production workflow manager;
- Assist collaborators with data access, analysis, and interpretation;
- Supervise and guide bioinformatics analysts/programmers;
- Participate in grant application writing;
- Publish results in scientific journals and give presentations at conferences.

Requirements

- PhD. in bioinformatics, computational biology, genetics, computer science or similar;
- 3 or more years work experience in Bioinformatics and Genomics with experience in cancer genomics;
- Experience managing and working with next generation sequencing data required;
- Extensive knowledge and experience in the use of existing bioinformatics tools and biological databases, as well as familiarity with cloud computing required;
- Proficiency in python and R required, and one or more programming languages such as Perl, Java, or C/C++ desirable, as well as willingness to learn new programming languages as necessary to collaborate at NYGC;
- Experience working in Linux and running tasks in a cluster environment (e.g. SGE) required;
- Experience working in teams centered around a biological question and with external collaborators required;
- Excellent written and verbal communication skills required;
- Experience with design of sequence analysis algorithms desirable.

About Our Organization

The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to hire and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

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