Bioinformatics Research Scientist

St. Jude Children’s Research Hospital
Job Location
Memphis, TN 38105
Job Description

Job Title: Bioinformatics Research Scientist
Department: Hematology
Job Number: 32874
Location: Memphis, TN 

St. Jude Children’s Research Hospital is a world-renowned institution that is recognized as one of the best places to work in the nation. As a premier center for research and treatment of childhood catastrophic diseases, we employ a diverse team of scientific and healthcare professionals dedicated to the promise of hope. Children from all 50 states and from around the world have come through the doors of St. Jude for treatment, and thousands more have benefited from our research.

SJCRH Computational Biology (Comp. Bio) Department is seeking a highly motivated bioinformatics research scientist to work on disease-related genetic studies in collaborative research projects with SJCRH investigators in the Departments of Cell and Molecular Biology, Oncology (Division of Cancer Predisposition) and Hematology. The Comp. Bio Department has a well-established track record in leading bioinformatics analysis for high-profile research investigations, such as the St. Jude/Washington University Pediatric Cancer Genome Project, which has resulted in multiple, high impact publications in the journals of New England Journal of Medicine, Nature, Nature Genetics, Nature Methods, JAMA and Cancer Cell.  CompBio provides a highly interactive teamwork environment, access to state-of-art computational infrastructure, well-established analytical pipeline, and deep experience in analyzing, managing, visualizing and delivering high-quality results for highly competitive projects. The bioinformatics research scientist will have an opportunity to work on large-scale discovery projects using the latest genomic sequencing technology including whole genome/exome sequencing, RNA-seq, CHIP-seq and MiSeq. The Department of Cell and Molecular Biology is committed to basic biological discovery and to understanding the molecular bases for neurodegenerative disorders. The Division of Cancer Predisposition in the Department of Oncology focuses on identifying, studying and managing patients and families with germline mutations that predispose to pediatric cancer and influence response to treatment. The Hematology Department performs cutting edge basic and translational research on normal and pathological blood cell formation, including the genetic diagnosis of non-malignant blood diseases including bone marrow failure and myeloproliferative syndromes. Research in these Departments has resulted numerous high profile studies published in journals including Nature, Nature Genetics, The New England Journal of Medicine, Cell, Cell Stem Cell, Developmental Cell, The Journal of Clinical Investigation and others. Researchers within SJCRH are highly collaborative and interactive, both within the Institution and with outside investigators. The specific areas of research will include projects to define and study germline and somatic mutations underlying the development of childhood cancers, non-malignant blood disorders and neurodegenerative diseases. Candidates with deep understanding of biological problems, critical thinking, and expertise in genomic data analysis are highly encouraged to apply for this position.


  • Ph.D. in Molecular Biology, Biochemistry, Computer Science, Statistics, Mathematics, Bioinformatics or related field required.
  • Ph.D. which must include research related to bioinformatics (such as analysis of sequence data, microarrays, SNPs, image data, proteomics data, or biological pathways; development of algorithms, statistical methods, or scientific software).
  • OR
  • If Ph.D. with no bioinformatics research, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required.
  • Experience with programming languages such as Perl, C, or Java required.
  • Experience with Python and knowledge on statistical analysis package such as R and Matlab is highly desired.





St. Jude Children’s Research Hospital is an Equal Opportunity Employer. St. Jude does not discriminate on the basis of race, national origin, sex, genetic information, sexual orientation, age, religion, disability, veteran’s status or disabled veteran’s status with respect to employment opportunities.  All qualified applicants will be considered for employment.  St. Jude engages in affirmative action to increase employment opportunities for minorities, women, veterans and individuals with disabilities.

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