Bioinformatics Research Scientist

St. Jude Children's Research Hospital
Job Location
Memphis, TN
Job Description

Job Title: Bioinformatics Research Scientist
Department: Computational Biology
Job Number: 32729
Location: Memphis, TN

St. Jude Children's Research Hospital, founded by the late entertainer Danny Thomas, is one of the world's premier centers for the research and treatment of pediatric cancer and other catastrophic childhood diseases. St. Jude is the first and only pediatric cancer center to be designated as a Comprehensive Cancer Center by the National Cancer Institute. Children from all 50 states and from around the world have come through the doors of St. Jude for treatment, and thousands more around the world have benefited from the research conducted at St. Jude - research that is shared freely with the global medical community. St. Jude is the only pediatric cancer research center where families never pay for treatments that are not covered by insurance. No child is denied treatment because of a family's inability to pay.

St. Jude Children’s Research Hospital’s Computational Biology Department is looking for a highly motivated bioinformatics research scientist as the key analyst for the institutional clinical genomics project. The Department has a well-established track record in leading bioinformatics analysis for high-profile genomic and translational research projects such as the St. Jude/Washington University Pediatric Cancer Genome Project which has resulted in multiple, high impact publications in the journals of New England Journal of Medicine, Nature, Nature Genetics, Nature Methods, JAMA and Cancer Cell. Computational Biology provides a highly collaborative teamwork environment, access to state-of-art computation infrastructure and visualization tools, highly automated analytical pipeline, and mentorship from senior scientists with deep experience in data analysis, data management and delivery of high-quality results for highly competitive projects. The bioinformatics research scientist will work on integrative analysis of whole-genome, whole exome and transcriptoming sequencing data to discover somatic and germline genetic alterations in pediatric cancer patients. The Bioinformatics Research Scientist will have the opportunity to collaborate with top-notch multi-disciplinary, translational researchers to explore the use of genetic data for precision medicine. This may include development of novel computational methods to facilitate clinical decision making, immunotherapy and pharmacogenomics. Candidates with deep understanding of cancer genomics or genetics, strong problem solving skills, attention to detail, critical thinking, and expertise in next-generation sequencing data analysis are highly encouraged to apply for this position.

• Ph.D. in Molecular Biology, Biochemistry, Computer Science, Statistics, Mathematics, Bioinformatics or related field required. Ph.D. which must include research related to bioinformatics (such as analysis of sequence data, microarrays, SNPs, image data, proteomics data, or biological pathways; development of algorithms, statistical methods, or scientific software).
• If Ph.D. with no bioinformatics research, then two (2) years of pre-or postdoctoral experience in Computational Biology or Bioinformatics research is required.
• Experience with programming languages such as Perl, C, or Java required.Experience with Python and knowledge on statistical analysis package such as R and Matlab is highly desired.



St. Jude Children’s Research Hospital is an Equal Opportunity Employer. St. Jude does not discriminate on the basis of race, national origin, sex, genetic information, sexual orientation, age, religion, disability, veteran’s status or disabled veteran’s status with respect to employment opportunities. All qualified applicants will be considered for employment. St. Jude engages in affirmative action to increase employment opportunities for minorities, women, veterans and individuals with disabilities.

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