Bioinformatics Analyst, Epigenomics

New York Genome Center
Job Location
101 Ave of the Americas
New York, NY 10013
Job Description

The New York Genome Center is looking for a highly motivated, detail-oriented individual to join our rapidly expanding informatics division in the bioinformatics and computational biology group. As Bioinformatics Analyst (Epigenomics), you will be responsible for the analysis of next-generation sequencing (NGS) data, including but not limited to chromatin immunoprecipitation and bisulfite sequencing. You will work as part of a team of analysts and scientists led by experienced bioinformatics scientists.


Job duties might include:

  • Analyze sequencing data using established workflows;
  • Perform appropriate QC measures;
  • Implement, execute and document data analysis pipelines and workflows;
  • Benchmark new tools for sequencing data analysis and propose improvements;
  • Develop and apply novel analysis approaches;
  • Assist and collaborate with internal and external researchers on analyses of NGS data;
  • Summarize results in written or oral reports for bioinformatics scientists and internal researchers;
  • Assist bioinformatics scientists in preparing text and figures for manuscripts and external presentations.

uired Skills

  • BS or MS degree with 3+ years work/research experience or PhD in epigenomics, functional genomics, biochemistry, molecular biology, bioinformatics, biostatistics, computer science, physics, mathematics or similar with demonstrable computational skills required;
  • In depth understanding of the biological principles related to epigenomics (post-translational histone modifications, DNA methylation, chromatin structure and accessibility, genetics, cis-regulation, etc.) and the analytical methodologies needed to analyze and integrate functional data types (ChIP-seq, methylC-seq, HumanMethylation450 arrays, DNase I hypersensitivity, ATAC-seq, RNA-seq, etc.)
  • Familiarity with relevant resources such as the Encyclopedia of DNA Elements (ENCODE) and the Roadmap Epigenomics Mapping Consortium (REMC)
  • Programming skills in R, Python, Perl, BASH or similar;
  • Programming skills in C++ or Java a plus;
  • Experience working in a Linux environment, experience with SGE preferred;
  • Team oriented with excellent written and verbal communication skills.
About Our Organization

The New York Genome Center (NYGC) is an independent, non-profit organization that leverages the collaborative resources of leading academic medical centers, research universities, and commercial organizations. Our vision is to transform medical research and clinical care in New York and beyond through the creation of one of the largest genomics facilities in North America, integrating sequencing, bioinformatics, and data management, as well as performing cutting-edge genomics research.

The New York Genome Center is a VEVRAA Federal Contractor. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, national origin, age, disability, or protected veteran status. The New York Genome Center takes affirmative action in support of its policy to and advance in employment individuals who are minorities, women, protected veterans, and individuals with disabilities.

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