Twist BioScience
Job Location
San Francisco, CA
Job Description

This position will play a key role in expanding Twist Bioscience’s variant library business and developing next generation variant library products and tools to support internal and external protein bioengineering and antibody discovery work. The successful candidate will be responsible for:

  • Collecting requirements from the biologists in the R&D team for programing needs with emphasis on variant library product line
  • Writing custom scripts for library design and data analysis with emphasis on NGS datasets
  • Packaging custom scripts into pipeline solutions
  • Collaborating with informatics group to convert R&D pipeline to production-scale pipeline, ensuring compliance with company-wide data and database structures and policies


  • Bachelor or Master degree in Computer Science, Computational Biology, Bioinformatics or related field
  • Proficiency in python, ruby, R, perl, or other high-level scripting language (Python highly preferred)
  • Familiarity with LINUX-based operating systems and shell scripting
  • Basic understanding of molecular biology and eager to learn
  • Experience designing and developing research pipeline solutions to handle large dataset
  • Experience with UI development for non-programing users
  • Familiarity with source control (git, subversion)
  • Experience in next generation sequencing data handling and analysis is a plus
How to Apply
About Our Organization

About Twist Bioscience

At Twist Bioscience, our expertise is accelerating science and innovation by leveraging the power of scale. We have developed a proprietary semiconductor-based synthetic DNA manufacturing process featuring a 10,000-well high throughput silicon platform capable of producing synthetic biology tools, including genes, oligonucleotide pools and variant libraries. By synthesizing DNA on silicon instead of on traditional 96-well plastic plates, our platform overcomes the current inefficiencies of synthetic DNA production, and enables cost-effective, rapid, high-quality and high throughput synthetic gene production, which in turn, expedites the design, build, test cycle to enable personalized medicines, pharmaceuticals, sustainable chemical production, improved agriculture production, diagnostics, biodetection and data storage. For more information, please visit Twist Bioscience is on Twitter. Sign up to follow our Twitter feed @TwistBioscience at

Twist Bioscience is an equal opportunity employer.

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