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Automation Engineer

Organization

Resilience

Job Location

9310 Athena Circle
San Diego, CA 92037
United States

Job Description

Position Summary

The Automation Engineer will be collaborating with others in Resilience to develop automation solutions. You will design, implement, and support our R&D into breakthroughs in biomanufacturing processes and our in-house instrument development supporting personalized medicine.  This role will be a key team contributor applying extensive knowledge of design principles and implementing complex automation solutions. General responsibilities include design concept generation, participating in and leading design reviews, developing and testing the work cell/solution. This is a high-impact technical role where you will collaborate across teams and provide an opportunity to lead the architecture and roadmap in executing and developing automation solutions.

 

Resilience is looking for smart, motivated engineers who enjoy taking on complex challenges, work well in an agile, dynamic environment, and care about high-quality engineering best practices.

 

Job Responsibilities:

  • Collaborate with experimental scientists to gather experimental workflow requirements to enable translating processes into automated workflows

  • Determine optimal equipment to purchase to meet internal needs

  • Work with integration partners to oversee larger-scale solutions coming to fruition

  • Create protocols/scripts to control automated lab equipment (liquid handling platforms / robotic arms / incubators etc.)

  • Track throughput needs for various workflows to identify times to transition from manual to semi-automated to fully automated to lights-out.

  • Understand what scientific risks a particular automation protocol may have and communicate those to scientific team members can monitor outputs/results accordingly (e.g., edge effects on a temperature block, shear stress with automated pipette tips of different orifices than in manual workflows)

  • Code software workflows to connect automation equipment to/from LIMS and other Cloud resources

  • Create and analyze Process Diagrams for workflows to increase robustness and identify potential points for improvement

  • Manage the operation of core automation resources: train users to repair instrument issues and apply continuous improvement principles to increase uptime at a reduced cost.

  • Contribute to the establishment of the group and individual objectives, priorities, and metrics

 

Qualifications:

  • Skilled in automating microplate workflows: pick and place, peel/seal, hit picking, miniaturization to 384/1536 well

  • Familiarity with Python or a similar object-oriented programming language

  • Excellent organizational skills; Able to manage multiple fast-paced projects simultaneously.

  • Ability to communicate effectively and professionally across various technical disciplines with a broad slate of stakeholders, including management, peers, and suppliers.

  • The initiative, curiosity, a bias for action, and a problem-solving attitude, and desire to bring innovative, simplified solutions to complex problems

  • Some background knowledge in molecular biology, cell biology, Next Generation Sequencing, wet-lab experimental procedures, and data analysis is a plus.

 

Experience:

  • BSc/MS: 5+ years of experience or Ph.D.: 2+ years of experience in an engineering or biological discipline

  • Minimum of 3 years developing automation solutions in biological laboratories

  • Experience developing automation solutions from early-stage concept to optimized, automated workflow.

  • Experience automating at least two of the following: NGS library prep, cell culture, cell-based assays, molecular biology, small-scale (1-40L) bioreactors

About Our Organization

Resilience (National Resilience, Inc.) is a first-of-its-kind manufacturing and technology company dedicated to broadening access to complex medicines and protecting biopharmaceutical supply chains against disruption. Founded in 2020, the company is building a sustainable network of high-tech, end-to-end manufacturing solutions to ensure the medicines of today and tomorrow can be made quickly, safely, and at scale.

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