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Research Specialist - Kingsley Lab

Organization

Howard Hughes Medical Institute (HHMI)

Job Location

Beckman Center
Stanford, CA 94305
United States

Salary

Competitive

Benefits

Full Benefits Package

Job Description

We are currently looking for a talented, resourceful Research Specialist to join the laboratory of Dr. David Kingsley at Stanford University.

The Kingsley lab uses a combination of genetic and genomic approaches to identify the detailed molecular mechanisms that control evolutionary differences in vertebrates.  The lab has developed innovative approaches to find the DNA changes responsible for dramatic differences in skeletal patterns, body shape, pigmentation differences, neurological traits, and disease susceptibility in stickleback fish, mice, and humans  By searching genomes for key changes, and then modeling the effects of these sequence changes in animal models, it is now possible to identify the molecular and developmental mechanisms underlying many classic biological traits that have evolved in natural species.  The lab’s work has also shown that evolution tends to use similar mechanisms repeatedly.  The lab is therefore applying fundamental principles identified in stickleback fish to many other organisms, including dramatic morphological skeletal, neurological, and disease traits that have evolved in the human lineage. More information about the Kingsley lab and it’s research can be found here:  https://kingsley.stanford.edu/

This is a dynamic position that will contribute to the Kingsley lab’s broad research and educational goals in evolutionary genetics, while also managing one’s own independent research project(s). The ideal candidate enjoys genetics, genomics, and bench research, has strong interpersonal skills, and has the ability to collaborate and work well with other lab team members in a highly interactive and supportive lab environment.

Essential Duties and Responsibilities

  • Manages one or more independent research projects studying the genetic basis of complex traits and diseases in vertebrates, using mice and cultured pluripotent cells from different species.

  • Oversees multiple strains in the lab’s mouse research colony, including multiple mouse models of genomic changes found in humans or other mammals

  • Coordinates with and trains lab members on specialized research techniques involving molecular biology and mouse prenatal and postnatal development.

  • Reviews research activities to determine where new information, methods, or collaborations could positively impact projects and improve efficiency of processes.

  • Serves as point person and schedule coordinator for specialized pieces of scientific equipment used for many developmental and morphological studies (such as cryostat microtome and microCT X-ray scanner).

  • Helps write and edit research publications and grants describing original research.

  • Presents own research updates and provides feedback on other team members research in  weekly interactive lab meetings.

Requirements

Qualifications

Education
A B.S. in genetics, genomics, molecular biology, evolutionary biology, or a closely related discipline is required. An advanced degree is preferred.

Experience

Hands-on experience with mouse research is required.

Hands-on experience with genetics, genomics, and molecular biology techniques is required.

Experience with cloning and building constructs is required.

Previous experience with genomic data analysis would be a plus.

Knowledge, Skills, and Abilities

Passion for both collaborative research and independent project work.

Excellent attention to detail and high degree of accuracy in research and writing.

Strong mentoring, teaching, and interpersonal skills with lab members at all career levels.

Strong verbal and written communication skills.

Ability to explore literature, think creatively, and plan effective experiments.

Ability to troubleshoot and problem solve while working on interesting research problems at the frontiers of current knowledge.

HHMI is an Equal Opportunity Employer

About Our Organization

Howard Hughes Medical Institute (HHMI) is an independent, ever-evolving philanthropy that supports basic biomedical scientists and educators with the potential for transformative impact. We make long-term investments in people, not just projects, because we believe in the power of individuals to make breakthroughs over time.

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