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Bioinformatics Scientist II


Cradle Genomics

Job Location

4755 Nexus Center Drive
San Diego, CA 92121
United States


  • Competitive salary
  • Equity compensation 
  • Generous 401(k) matching program 
  • Medical, dental, and vision insurance 
  • Free gym membership 
  • Flexible PTO 
  • Kombucha and cold brew on tap 
  • And more! 

Job Description

Cradle Genomics is currently seeking a Bioinformatics Scientist with experience in next-generation sequencing (NGS) data and a strong interest in quantitative biology and algorithm development. The Bioinformatics Scientist will evaluate, develop, validate, and implement NGS data analysis enhancements for test optimization, including bioinformatics analysis pipelines, testing/validation scripts, and other tools associated with non-invasive prenatal testing (NIPT).



  • Develop and implement methods/algorithms/tools for optimizing clinical test performance
  • Analyze DNA sequencing data and work with our team of scientists to answer specific biological questions
  • Provide technical guidance in the design and analysis of experiments during all phases of clinical test development
  • Effectively communicate data analysis methods and results to non-computational teams and management
  • Refine algorithms and tools for DNA sequencing data analysis and propose improvements
  • Produce high quality written documentation including study protocols, data analysis plans and reports
  • Provide troubleshooting and maintenance supports for bioinformatics pipeline
  • Provide training/guidance/expertise to team members, as needed
  • Contribute to experimental design, quality control, and statistical analysis

Qualifications and Experience:

  • PhD in Bioinformatics, Computer Science, Engineering, Biochemistry or similar field required
  • Minimum of 2+ years of relevant work experience in the industry
  • Deep understanding of DNA sequencing data and its analysis (mapping, variant calling, etc.). Specific experience with the analysis of NIPT data preferred
  • Experience programming in Python, Perl, Java and/or R
  • Experience using Linux command-line tools and writing shell scripts
  • Experience applying statistics/biostatistics to biological datasets
  • Experience analyzing, troubleshooting and problem-solving technical issues involving complex data
  • Knowledge of the key public reference databases for clinical variation data
  • Ability to work independently as well as part of a team
  • Ability to summarize results verbally and in written form
  • Self-motivated and detail-oriented

How to Apply

Apply to our job post on LinkedIn: here

About Our Organization

At Cradle Genomics, our mission is to provide knowledge that helps every pregnancy. We're dedicated to the transformation of non-invasive prenatal testing (NIPT) by offering the most comprehensive fetal genetic analysis and pregnancy health screening solutions at the earliest stages of pregnancy. Cradle Genomics is newly formed with our headquarters based in San Diego. Cradle tests are based on the genetic analysis of fetal cells quickly collected during a first trimester visit with no risk to the mother or developing fetus. We are passionate about improving patient care and enabling global access to the best possible prenatal solutions.

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