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Translational Research Scientist - Cancer Diagnostics

Organization

The Broad Institute of MIT & Harvard

Job Location

415 Main Street
Cambridge, MA 02142
United States

Benefits

The Broad Institute is committed to providing its employees with a competitive compensation and benefits package. At Broad we recognize the need for our employees to have a balance between work and personal life. To that end, our benefit plans and options reflect our desire to promote an environment that supports the health and general well-being of our employees.

Our BroadLife office helps make life work for all members of Broad's diverse community by offering resources that make it easier to integrate work, personal and family commitments. BroadLife hosts regular seminars, briefings and discussion groups to provide strategies, tips, and information to help you deal with a diverse array of work-life issues. 

Our comprehensive benefit plans are designed to provide you with affordable health and dental care, continuation of salary in the event you become disabled and cannot work, generous paid time off, financial security for your survivors, a retirement savings plan, tuition assistance, pre-tax basis flexible spending accounts, several Broad-provided benefits that eligible employees are automatically enrolled in, and a variety of other work/life programs designed to balance your work and personal life.

Job Description

The Broad Institute of MIT and Harvard is seeking a highly motivated individual for an exciting Research Scientist position within the Gerstner Center for Cancer Diagnostics and the Broad’s Cancer Program. This position affords the opportunity to establish the clinical validity for new diagnostic methods from impactful clinical studies.

The newly formed Center aims to develop blood biopsies among other cancer diagnostics that stand to benefit millions of patients worldwide. Learn more in a Broad news storyvideo, and Boston Globe report. 

The successful candidate will be principally responsible for applying new technologies such as our ultrasensitive blood test for minimal residual disease (e.g. Parsons et al Clinical Cancer Research 2020, Gydush et al BioRXiv 2020, etc.) to impactful clinical studies. You will be expected to bring deep expertise in next generation sequencing and related methods, with the ability to apply high complexity molecular assays to clinical specimens.

Responsibilities include implementing novel molecular assays, optimizing lab protocols, coordinating with clinical collaborators to receive and process clinical specimens, and working with our computational scientists to analyze and interpret the results from clinical studies. In addition, you will be expected to bring strong organizational and communication skills to effectively coordinate multiple clinical studies from start to finish, resulting in publication.

This exciting position affords significant growth opportunity in a fast-paced research environment and is perfect for someone who is looking to hone scientific and leadership skills, and to gain experience as a translational scientist. Our team includes scientists, engineers, medical oncologists, and computational biologists, spanning the Broad Institute, MIT, Harvard, and Harvard-affiliated hospitals; the successful candidate will gain exposure to cutting-edge science through meetings, symposia, and interactions with devoted colleagues and collaborators.

CHARACTERISTIC DUTIES

  • Implements high complexity molecular assays and applies them to clinical samples

  • Develops detailed research plans and contributes to grant applications as needed

  • Coordinates clinical studies from start to finish with the goal to publish findings

  • Keeps everybody informed and engaged; helps to write and submit papers

  • Attends, presents, and leads discussions at routine team meetings

Requirements

QUALIFICATIONS

  • Ph.D. (and/or MD) in cancer biology, molecular biology, or related field required

  • Prior experience with next generation sequencing and related methods required

  • Publication track record including high complexity molecular assays preferred

  • 3+ years of post-doctoral or professional experience preferred

  • Excellent written, documentation, and oral communication skills

  • Strong interpersonal, organizational, analytical, and leadership skills

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

About Our Organization

The Broad Institute of MIT and Harvard is a research organization that convenes a community of researchers from across many disciplines and partner institutions—MIT, Harvard, and Harvard-affiliated hospitals. 

Based in Cambridge, Massachusetts, the Broad Institute was founded in 2004 to fulfill the promise of genomic medicine—three years after completion of the Human Genome Project, which Broad scientists helped create and lead. Our origins are rooted in genomics, and as biomedical research and knowledge have expanded since 2004, so have we. Our researchers are deeply collaborative, nimbly launching innovative, high-risk projects at every scale, inventing new technologies, building and implementing computational tools, developing new therapeutics to advance into the clinic, mentoring and training the next generation of scientists, and sharing our data and tools openly to enable breakthroughs anywhere. 

Accelerating biomedical research and improving human health require diversity of all kinds in our community—in education, training, background, perspectives, interests, and identity—because it expands our creativity in how we approach problems and find solutions. Broad aims to ensure that the benefits of genomic medicine are shared by all. 

We tackle challenges in human health by: 

Illuminating human disease
We use systematic, unbiased approaches to identify the root biological causes of disease and find new opportunities for therapeutic intervention.

Reading and editing genomes
We generate a whole human genome’s worth of genetic data every few minutes, read gene expression patterns in tissues and in millions of single cells, and use gene editing to create disease models and dissect cell circuitry.

Sharing data and tools
We make discoveries, data, tools, technologies, and knowledge freely available. We work with industry partners to ensure these innovations benefit patients.

Building communities
We create, steward, and partner in international collaborations with scientists around the world. We work with researchers and patients to tackle important challenges in biomedicine and find innovative, high-impact solutions.

Developing diagnostics and treatments
We are revealing deep biological insights into the causes of disease, which are leading to new ways to monitor, diagnose, and treat patients with greater precision. 

Collaborating, innovating, and empowering
We strive to build an inclusive community that empowers and taps into the full potential of every Broadie.

Career Blog headlines

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The Pandemic and Women in STEM

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Missing from the Top

A new report finds that women, especially women of color, are missing among the high-earners at research universities in the US, the Chronicle of Higher Education writes. 

Time Lost

Researcher-parents, especially mothers of small children, have lost research time during the COVID-19 pandemic, according to the Chronicle of Higher Education.