Research & Discovery

hookworm

Genomic and transcriptomic analysis of the hookworm genome revealed timing of gene expression throughout its parasitic lifecycle.

The group's effort looked at the development steps required for successful implementation of MRM-MS assays as well as promising technical advances.

The firm is now clinically validating a mass spec-based test for quantifying native insulin and its therapeutic analogs and another test for type 2 diabetes. 

The findings demonstrate how one type of posttranscriptional modification gives RNA-binding proteins access to previously inaccessible regions of the mRNA.

The approach brings together the spatial resolution of optical microscope and the rich molecular information generated by imaging mass spectrometry.

In PLOS this week: new gene linked to ocular coloboma, new statistical model for interrogating gene expression networks, and more.

With a new collection, PLOS highlights negative results it has published.

A pair of researchers examines political leanings and views on genomics, finding more of a role for optimism and pessimism in people's views.

The genome of the carnivorous bladderwort is smaller than many other plant genomes, but it still holds on to important genes.