Proteomics & Protein Research | GenomeWeb

Proteomics & Protein Research

The test is designed to replace gel electrophoresis assays currently used for measuring M-proteins, biomarkers for plasma cell diseases such as multiple myeloma.

The finding that many antigenic peptides presented by HLA-I  have been spliced by the proteasome has implications for research in cancer immunotherapy and autoimmunity.

Using mass spec and small hairpin RNA, they built a map of ALK signaling and identified proteins that could sensitize tumor cells to inhibitor treatment.

Their method uses the increased separation provided by FAIMS upfront of mass spec analysis, to reduce precursor interference in isobaric tagging experiments.

Singapore Eye Research Institute's Roger Beuerman wants to bring point-of-care eye diagnostics to the ophthalmologist's office.