Proteomics & Protein Research

DSysMap combines mutation information with protein interaction data to provide a clearer picture of functional changes associated with the development of complex diseases.

The group's effort looked at the development steps required for successful implementation of MRM-MS assays as well as promising technical advances.

The firm is now clinically validating a mass spec-based test for quantifying native insulin and its therapeutic analogs and another test for type 2 diabetes. 

The approach brings together the spatial resolution of optical microscope and the rich molecular information generated by imaging mass spectrometry.

Researchers have developed a mathematical framework for forming disease modules based on protein interaction profiles and GWAS data.