The investigators used the technique to identify two novel secretome targets and then confirmed them to be elevated in the blood of women with cancer.
The study, funded last month by the NIH, will use SRM-MS to identify proteins from a subset of promising pathways that are associated with DKD patients' progression to end-stage disease.
The registry is expected to yield a "validated, semi-quantitative risk assessment algorithm that will assist physicians in managing patients at risk for ovarian cancer."
The deal gives EMD Millipore control of Singulex's single-molecule counting technology for research applications.
The company plans to launch the test, which uses serial CA-125 measurements, in theUKthis summer and in theUSlater this year.
In Science this week: swapping yeast genes with human orthologs to study conservation of function, and more.
Hong Kong is using DNA phenotyping to shame litterers.
A study appearing in Cell suggests some metastatic castration-resistant prostate cancer patients could benefit from PARP inhibitor therapy.
NIH's Francis Collins writes that scientific advances are poised to help populations all over the world, but more scientists are needed to keep the momentum.