NEW YORK (GenomeWeb) – Mount Sinai Health System today announced the Sanford J. Grossman Charitable Trust has committed up to $3 million to establish a new center at the Icahn School of Medicine at Mt. Sinai to research irritable bowel disease with a focus on Crohn's disease.
The Grossman trust has committed $1 million so far and will provide another $2 million based on the achievement of certain milestones. The center, called the Dr. Sanford J. Grossman Center for Integrative Studies in Inflammatory Bowel Disease, will be headed by Judy Cho, a professor of translational genetics and medicine and vice chair of translational genetics and gastroenterology at Mt. Sinai.
The center's focus will be on developing personalized medicine for treating Crohn's disease by parlaying expertise in genetics, pathology, radiology, immunology, and gastroenterology. Investigators will work to establish methods of more precise pathologic and radiologic evaluation, improved tissue banking, genetic and cellular analysis, and integrating basic science and clinical discoveries, Mt. Sinai said.
Grossman said that Mt. Sinai has unique data, including information about genomics and family history, clinical symptoms and histology, pathology reports on resected gut tissue, and radiology.
"My hope is that the integration and analysis of this data will enable a better understanding of the manifestations and natural histories of Crohn's disease, and with that knowledge, therapies will be developed to beneficially alter the natural course of the disease," Grossman said in a statement. "At the very least, I hope that there will be a better understanding of the biological processes that lead to various types of structure formation, and some suggestions as to how strictures can be prevented."