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Cincinnati Children's Awarded $5.7M NIH Grant to Manage Pediatric Cardiovascular Disease Consortia

This article has been updated to reflect the correct term of the grant project.

NEW YORK (GenomeWeb) – The Cincinnati Children's Hospital Medical Center (CCHMC) has been awarded a five-year grant from the National Institutes of Health to act as an administrative coordinating center for members of the Cardiovascular Development Consortium (CvDC) and Pediatric Cardiac Genomics Consortium (PCGC).

The PCGC was established to bring together multidisciplinary research teams and scientific core facilities that would study genetic variants involved in congenital heart disease and translate those findings into improved therapies, prevention strategies, and risk stratification. The CvDC generates and shares data about the molecular networks and pathways involved in cardiovascular development. Both projects were launched by NIH's National Heart, Lung, and Blood Institute.

The consortia interact with each other and the NHLBI's Pediatric Heart Network (PHN), which provides clinical and observational study experts, as part of the institute's Bench-to-Bassinet Program.

With the grant funding, which is worth $5.6 million in the first year, the CCHMC will provide the infrastructure to support interactions between the CvDC, the PCGC, and the PHN, as well as facilitate the translational research process for pediatric cardiovascular clinical care problems, according to the grant's abstract. It will also promote standards required for data integration and sharing to enable reproducibility of consortia members' results.