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Accelerate Dx, Denver Health Medical Center Awarded $5M for Microbial MDx Development


NEW YORK (GenomeWeb) – The National Institutes of Health has awarded Denver Health Medical Center and Accelerate Diagnostics a five-year, $5 million grant to develop a test for detecting common bacteria directly from blood, the company announced on Friday. 

The test will also be developed to detect antibiotic resistance and to provide results in less than three hours. The initial focus of the project will be on carbepenem-resistant Enterobacteriaceae, the partners said. 

Accelerate's ID/AST System will be used for the study. Combining rapid genomic identification and high-speed phenotypic susceptibility, the platform can extract single bacteria cells from a patient's blood. Accelerate noted that current methods can take up to three days to grow a bacterial sample and to test which antibiotics are effective. 

Its CEO Lawrence Mehren recently said that Accelerate plans to launch its platform in Europe this year and to start clinical trials for the system in preparation of a 510(k) submission to the US Food and Drug Administration. 

The Scan

Interfering With Invasive Mussels

The Chicago Tribune reports that researchers are studying whether RNA interference- or CRISPR-based approaches can combat invasive freshwater mussels.

Participation Analysis

A new study finds that women tend to participate less at scientific meetings but that some changes can lead to increased involvement, the Guardian reports.

Right Whales' Decline

A research study plans to use genetic analysis to gain insight into population decline among North American right whales, according to CBC.

Science Papers Tie Rare Mutations to Short Stature, Immunodeficiency; Present Single-Cell Transcriptomics Map

In Science this week: pair of mutations in one gene uncovered in brothers with short stature and immunodeficiency, and more.