The researchers plan to use their method to study neural transmission in disease and will also offer the technique as a service for other neuroscience labs.
The new method takes expressed mRNA and turns it into guide sequences for CRISPR/Cas9 knockout screening when bioinformatics-based design isn't an option.
The findings could lead to a more personalized approach for preventing asthma in children, the researchers suggested.
The proteomic study, which built on past findings that HER2-negative tumors generate HER2-positive cells after treatment, suggests a role for combination therapy.
Proponents believe the Million European Genomes Alliance will spur research, stimulate the life sciences economy, and ultimately improve clinical care.
Being born premature shouldn't mean infants with high blood sugar levels don't undergo genetic testing for neonatal diabetes, a study in Pediatrics says.
In Cell this week: phosphoproteomic patterns in prostate cancer, effect of gene expression on fitness in yeast, and more.
Scripps Research Institute investigators peer back at the RNA world.
In PNAS this week: chromosome instability in S. cerevisiae, structural differences and sequence divergence in rice, and more.