A gene-environment analysis involving 10,346 twins suggests parents are more restrictive when feeding children who have a genetic propensity for weight gain.
Researchers at the University of Copenhagen used mass spectrometry to analyze dental plaque from 21 individuals recovered from a medieval Danish gravesite.
With sequence data for 910 African individuals, researchers found more than 296 million bases of sequence not represented in the human reference genome GRCh38.
A study presented at the National Society of Genetic Counselors annual meeting last week analyzed how counseling sessions affected patients on five measures.
While next-generation sequencing (NGS) has driven recent advances in precision oncology research, it often falls short when identifying the molecular mechanisms underlying many malignancies. As a result, alternative NGS-based approaches are needed to identify oncogenic drivers and potential drug targets.
Rhythm Pharmaceuticals and Genomenon will discuss their efforts to assemble a database of mutations associated with rare genetic disorders of obesity, and how this was optimized to facilitate a deep understanding of the variant landscape of melanocortin-4 receptor (MC4R)-pathway genes. This database may help identify MC4R-pathway deficient individuals who might benefit from future precision therapies.
