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Wash U to Use Bruker Technology for Proteomics

NEW YORK (GenomeWeb News) – Bruker Daltonics announced today that researchers from Washington University have ordered a Bruker 12 Tesla FTMS and a new Bruker ultra-high-resolution time-of-flight mass spectrometer maXis for top-down proteomics and other projects.
The company said that Washington University researcher Michael Gross ordered the technology and will be working in collaboration with Reid Townsend, director of Washington University’s proteomics facility core labs.
Along with the top-down proteomics applications, in which intact proteins are measured to determine molecular weights and then fragmented and measured again with FTMS, the researchers also plan to use the Bruker technology for small molecule mass formula determination and protein structure studies.
Bruker and Gross have also reached an agreement giving Gross’ lab early access to Bruker’s newly developed, front-end electron transfer dissociation module for FTMS. This ETD method is designed to be a sensitive and easy method for fragmenting peptides and proteins and preserving post-translational modifications.

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