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UniProt, European Bioinformatics Institute, Swiss Institute of Bioinformatics, Protein Information Resource, Thermo Electron, Blueprint Initiative


The UniProt consortium consisting of the European Bioinformatics Institute, the Swiss Institute of Bioinformatics and the Protein Information Resource announced on Monday the launch of UniProt Release 2.5, a catalog of information on proteins. Monday. UniProt 2.5 consists of 1,559,136 entries. It can be accessed from the web at and downloaded from

Thermo Electron has incorporated Highly-Selective Reaction Monitoring into its Finnigan TSQ Quantum family of triple quadrupole mass spectrometers. This analytical application will help to further eliminate chemical noise and generation of false positives, and will allow for lower detection limits.

By incorporating H-SRM, Thermo’s quadrupoles are capable of higher tolerance levels without any significant loss of ion transmission. While the less advanced Selective Readction Monitoring technique selects precursor ions with a mass tolerance of +/- 0.5 m/z or higher, H-SRM can select precursor ions with a mass tolerance of +/- 0.1 m/z or less.

The Blueprint Initiative research program announced the release of significant upgrades to its Biomolecular Interaction Network Database this week. The new BIND 3.5 is optimized for searching and data retrieval. It features a dynamic, collapsible HTML page that eliminates the use for pop-up windows, and an accelerated, simplified search process powered by the open-source Apache Jakarta Lucene project.


The Scan

mRNA-Based Vaccine on the Way in China

China may soon have its own mRNA-based vaccine, according to Nature News.

Arranged Killing, Fraud Alleged by Prosecutors

The Wall Street Journal reports that prosecutors allege that the co-founder of a biotech arranged to have a business associate who threatened to expose him as a fraud killed.

Whirlwind Decade of CRISPR

The New York Times looks back at the 10 years since the University of California, Berkeley's Jennifer Doudna and her colleagues published their CRISPR paper.

PNAS Papers on Blue Cone Monochromacy Structural Variants, HIV-1 Mutant, T-ALL

In PNAS this week: structural variants linked to blue cone monochromacy, HIV-1 variants affecting the matrix protein p17, and more.