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UK Nonprofit Babraham Institute to Lead $2.4M Proteomics Consortium

NEW YORK (GenomeWeb News) — The British nonprofit Babraham Institute will coordinate a European Commission-sponsored proteomics research initiative that includes a large group of International research teams, the Institute said yesterday.
 
The ProteomeBinders initiative, which will spend  €1.8 million ($2.4 million) over four years among 26 partnering organizations in Europe and two in the United States, “sets the stage for an open-access resource of binding molecules directed against the entire human genome.”
 
The initial funding will be provided by the European Commission’s 6th Framework Program.
 
Babraham said the consortium will integrate “existing infrastructures,” review technology and high-throughput methods, standardize tools and applications, and establish a database.
 
The Institute said the program will aim to “understand how the information encoded within the genome, and expressed as the proteome, choreographs the biological organizations of cells, tissues and organisms.”
 
Mike Taussig, head of the institute’s Technology Research Group, said achieving this goal will require a “comprehensive, standardized collection of specific protein binding molecules.” To do this, he added, the partnership will explore binder types such protein scaffolds, nucleic acids, peptides, and other chemicals. He said these alternatives hold “significant advantages over antibodies.”
 
In the end, Taussig said, ProteomeBinders will attempt to “provide the tools required to detect and characterize all the relevant human proteins in tissues and fluids in health and disease.”

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