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Thermo Fisher Supplying Products for ISB's Proteome Map

By a GenomeWeb staff reporter

NEW YORK (GenomeWeb News) – Thermo Fisher Scientific today said it will be providing novel protein research products to the Institute for Systems Biology in support of its Human Proteome MRMAtlas.

The MRMAtlas is being led by Robert Moritz, associate professor and proteomics director at ISB, and Ruedi Aebersold, a professor of molecular systems biology at the Swiss Federal Institute of Technology and the University of Zurich. It aims to create a database containing at least four proteotypic peptides for each of the estimated 25,000 proteins encoded by human genes, by using mass spectrometry techniques selected-reaction monitoring, or SRM, and multiple-reaction monitoring, or MRM.

When completed, the atlas is anticipated to increase the speed and reduce the cost of biomarker discovery and analysis.

The two-year project is expected to use more than 100,000 synthetic peptides manufactured by Thermo Fisher, the company said in a statement. In addition, Moritz will use thousands of custom HeavyPeptide AQUA standards from Thermo Fisher to measure the abundance of natural peptides and to develop precise quantitative MRM/SRM assays.

The company will create a catalog of HeavyPeptide AQUA standards used in the assays for other scientists to use, Thermo Fisher said.

The MRMAtlas is being funded with a $2.7 million grant from the National Human Genome Research Institute and a €2.7 million ($3.3 million) contribution from the European Research Council.

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