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Thermo Fisher Scientific, Matrix Science, Shimadzu, AnaSpec

Thermo Fisher Scientific this week said it has integrated Matrix Science’s Mascot search engine for protein identification with its BioWorks software. The integration will allow users to consolidate results from the two search engines and cross-validate them. In a statement, Thermo Fisher said that the Sequest search engine, a component of BioWorks, and Mascot are the “two most widely accepted search engines” for protein identification and post-translational modification characterization.

Shimadzu Scientific Instruments last week said it will launch the Axima MALDI TOF mass specseries at Pittcon. The series comprises of the Performance, Confidence, and Assurance instruments. At the conference being held in March in New Orleans, the company also will unveil its Prominence nano HPLC at Pittcon in March. The instrument delivers “exact flow rates via two LC-20AD nano pumps,” the company said in a statement.


AnaSpec this week introduced its HABA Biotin Quantitation Kits for measuring molar ratio of biotin to protein on biotinylated conjugates. The kits are available in two sizes, 120 assays and 500 assays. Avidin and HABA at an “optimal” ratio are included in the assay kits, which have a linear range of 2 to 16 micromoles.

The Scan

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.

Fragile X Syndrome Mutations Found With Comprehensive Testing Method

Researchers in Clinical Chemistry found fragile X syndrome expansions and other FMR1 mutations with ties to the intellectual disability condition using a long-range PCR and long-read sequencing approach.

Team Presents Strategy for Speedy Species Detection in Metagenomic Sequence Data

A computational approach presented in PLOS Computational Biology produced fewer false-positive species identifications in simulated and authentic metagenomic sequences.

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.