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Thermo Electron, ProtoNet, Aureus Pharma

Thermo Electron announced the launch of its LTQ FT Ultra, a next-generation hybrid FTICR mass spectrometer. The instrument “analyzes complex matrices and large molecules with independent sub ppm mass accuracy, ultra-high resolution in excess of 750,000 and improved detection circuitry,” the company said this week in a press release.
Equipped with a novel ICR cell design, the Ultra Cell, which improves sensitivity and widens the dynamic range to beyond 4,000, all on LC timescale, the LTQ FT Ultra is suited for top-down and bottom-up proteomics and metabolomics, the company said.

ProtoNet has released its ProtoNet version 4.5, an automatic classification of protein sequences based on a hierarchical clustering method. The new version provides a classification for all proteins and supports TrEMBL entries, the company said last week in a press release.


Aureus Pharma announced it has released its AurSCOPE Kinase Knowledge database containing biological data obtained from scientific journals and patents.

The Scan

Genetic Tests Lead to Potential Prognostic Variants in Dutch Children With Dilated Cardiomyopathy

Researchers in Circulation: Genomic and Precision Medicine found that the presence of pathogenic or likely pathogenic variants was linked to increased risk of death and poorer outcomes in children with pediatric dilated cardiomyopathy.

Fragile X Syndrome Mutations Found With Comprehensive Testing Method

Researchers in Clinical Chemistry found fragile X syndrome expansions and other FMR1 mutations with ties to the intellectual disability condition using a long-range PCR and long-read sequencing approach.

Team Presents Strategy for Speedy Species Detection in Metagenomic Sequence Data

A computational approach presented in PLOS Computational Biology produced fewer false-positive species identifications in simulated and authentic metagenomic sequences.

Genetic Risk Factors for Hypertension Can Help Identify Those at Risk for Cardiovascular Disease

Genetically predicted high blood pressure risk is also associated with increased cardiovascular disease risk, a new JAMA Cardiology study says.