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Tecan US, Molecular Devices, Agilent Technologies, MiraiBio, Guava Technologies, BioTrove, Aclara BioSciences, Genetix, Nonlinear Dynamics, Amersham Biosciences, Novagen, Qiagen

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Many new products with proteomics applications were introduced at the Drug Discovery Technology 2003 conference this week. For a complete list of products, companies, and applications see the table on page 8. The following companies released new products at DDT: Tecan US, Molecular Devices, Agilent Technologies, MiraiBio, Guava Technologies, BioTrove, Aclara BioSciences, and Genetix.

 

Nonlinear Dynamics of Newcastle upon Tyne, UK, last week released TotalLab, an automated quantitative analysis system for 1D gels, arrays, colony counting, and general image analysis. Nonlinear offered a demonstration of the system at DDT this week.

 

Amersham Biosciences last week introduced CyDye DIGE Fluor Labelling Kit for Scarce Samples, an addition to its CyDye DIGE Fluor line of dyes for prelabeling proteins for 2D gel analysis. The new product enables researchers to label as little as 5 µm of sample for use with Amersham’s Ettan imaging system. The product is designed to detect very small protein abundance differences.

Amersham also introduced Ettan Sample Preparation Kits and Reagents, an addition to its Ettan line of proteomics products. The new elements of the kit include an albumin and IgG removal kit for high abundance protein removal (see Agilent story, p. 1), a 2D fractionation kit, and some basic chemicals and reagents. The products together remove nucleic acids, carbohydrates, lipids, and high abundance proteins.

 

Novagen has released a new protein transfection reagent called ProteoJuice. ProteoJuice delivers intact proteins to the inside of mammalian cells for the study of protein-protein interactions, protein turnover, cell signaling pathways, apoptotic pathways, and transcription factor-mediated gene regulation. ProteoJuice can deliver proteins up to 465 kDa by forming non-covalent interactions with the protein of interest.

 

Qiagen this week announced the release of its Two-Step Affinity Purification System for the purification of recombinant proteins from eukaryotic cell lysates. The system includes expression vectors, purification matrices, and antibodies.

The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.