Using yeast protein arrays made by Invitrogen, scientists at Yale have mapped over 4,000 different phosphorylation events involving 82 yeast kinases.
The study, published in last week's Nature, is the first one to use protein chips to identify phosphorylation events in a high-throughput, large-scale manner. Prior to this study, only about 160 interactions between yeast kinases and their targets had been identified, according to the scientists.
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