Tadpole-Shaped Protein-DNA Chimeras Allow for Detection of Very Low Abundance Proteins | GenomeWeb

Researchers at the Molecular Sciences Institute in Berkeley, Calif., have come up with a way to detect very low-abundance proteins by using tadpole-shaped protein-DNA chimeras which can be amplified using PCR.

According to Roger Brent, the director of the laboratory where the studies were conducted, the protein-DNA tadpoles can offer a limit of detection that is 109 lower than the traditional ELISA approach.

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