Sophisticated Separation


The origins of chromatography can be traced back to the beginning of the 20th century when Russian scientist Mikhail Tsvet used columns of calcium carbonate to separate plant pigments for his research on chlorophyll. Later in the 1940s and 1950s, partition chromatography was developed, which in turn led to various other separation methods — including high-performance liquid chromatography, a technology that has undergone a steady evolution for the last 25 years and which, when coupled with mass spectrometry, helped make proteomics and metabolomics research possible.

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