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Signet Laboratories, Apolipoprotein J, GE Healthcare, Waters, LICOR


Signet Laboratories announced last week the availability of an antibody to Apolipoprotein J, a protein implicated in neurological disorders such as Alzheimer’s Disease, Down’s syndrome, and transmissible spongiform encephalopathies, among others.

“Reserach has demonstrated that Apo-J is involved in the process of beta amyloid aggregation in vitro and in vivo, but the method by which the aggregation is affected has remained largely elusive,” said Joe Bertelsen, Neuroscience Product Manager for Signet. “Signets’ new Apo-J, in addition to Signet’s existing panel of neuroscience antibodies, gives researchers a powerful tool.”

In addition to its function in neurological disorders, Apo-J is also implicated in prostate cancer, pancreatic cancer, large cell lymphoma and diabetes.

GE Healthcare has introduced its AKTAxpress TWIN, the second in a series of protein-purification systems to deliver fully-automated, multi-step purification of His- and GST-tagged proteins. The product is a smaller version of GE Healthcare’s AKTAxpress, which is a high-throughput protein purification system.

Waters announced this week the introduction of its Empower Chromatography Software to provide support for its Agilent 1100 Series Photodiode Array Detector. The software is designed to allow scientists to confidently identify sample components and verify spectral homogeneity by using sophisticated algorithms for peak purity and library matching, the company said.

LICOR announced this week the introduction of its new Aerius Automated Infrared Imaging System designed for protein discovery using infrared plate-based assays. The Aerius builds upon LI-COR's Odyssey two-channel infrared detection system by adding a fast microplate reader capable of handling up to 30 microplates in a single run.

The Scan

Alzheimer's Risk Gene Among Women

CNN reports that researchers have found that variants in MGMT contribute to Alzheimer's disease risk among women but not men.

Still Hanging Around

The Guardian writes that persistent pockets of SARS-CoV-2 in the body could contribute to long COVID.

Through a Little Spit

Enteric viruses like norovirus may also be transmitted through saliva, not just the fecal-oral route, according to New Scientist.

Nature Papers Present Method to Detect Full Transcriptome, Viruses Infecting Asgard Archaea, More

In Nature this week: VASA-seq approach to detect full transcriptome, analysis of viruses infecting Asgard archaea, and more.