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Signet Laboratories, Apolipoprotein J, GE Healthcare, Waters, LICOR


Signet Laboratories announced last week the availability of an antibody to Apolipoprotein J, a protein implicated in neurological disorders such as Alzheimer’s Disease, Down’s syndrome, and transmissible spongiform encephalopathies, among others.

“Reserach has demonstrated that Apo-J is involved in the process of beta amyloid aggregation in vitro and in vivo, but the method by which the aggregation is affected has remained largely elusive,” said Joe Bertelsen, Neuroscience Product Manager for Signet. “Signets’ new Apo-J, in addition to Signet’s existing panel of neuroscience antibodies, gives researchers a powerful tool.”

In addition to its function in neurological disorders, Apo-J is also implicated in prostate cancer, pancreatic cancer, large cell lymphoma and diabetes.

GE Healthcare has introduced its AKTAxpress TWIN, the second in a series of protein-purification systems to deliver fully-automated, multi-step purification of His- and GST-tagged proteins. The product is a smaller version of GE Healthcare’s AKTAxpress, which is a high-throughput protein purification system.

Waters announced this week the introduction of its Empower Chromatography Software to provide support for its Agilent 1100 Series Photodiode Array Detector. The software is designed to allow scientists to confidently identify sample components and verify spectral homogeneity by using sophisticated algorithms for peak purity and library matching, the company said.

LICOR announced this week the introduction of its new Aerius Automated Infrared Imaging System designed for protein discovery using infrared plate-based assays. The Aerius builds upon LI-COR's Odyssey two-channel infrared detection system by adding a fast microplate reader capable of handling up to 30 microplates in a single run.

The Scan

Renewed Gain-of-Function Worries

The New York Times writes that the pandemic is renewing concerns about gain-of-function research.

Who's Getting the Patents?

A trio of researchers has analyzed gender trends in biomedical patents issued between 1976 and 2010 in the US, New Scientist reports.

Other Uses

CBS Sunday Morning looks at how mRNA vaccine technology could be applied beyond SARS-CoV-2.

PLOS Papers Present Analysis of Cervicovaginal Microbiome, Glycosylation in Model Archaea, More

In PLOS this week: functional potential of the cervicovaginal microbiome, glycosylation patterns in model archaea, and more.