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Sigma-Aldrich, Elchrom Scientific

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Sigma-Aldrich announced this week the launch of its Panorama Human p53 Protein Functional Microarray. Developed by Procognia and distributed exclusively by Sigma-Aldrich, the p53 protein microarray contains wild type human p53 and 49 of its variants. Each variant contains a mutation or single nucleotide polymorphism that results in an amino acid change or a truncation. The array is based on a novel and proprietary technology that ensures the protein is correctly folded and confers full functionality, the company said.


Elchrom Scientific introduced this week its Blot-EX — a new non-acrylmaide, not-toxic, high resolution electrophoresis precast hydrogel that was designed to increase protein transfer efficiency during Western blotting.

According to the Cham, Switzerland-based company, Blot-EX offers overall recovery efficiency of up to 90 percent, which can be obtained in less than 10 minutes — a significantly reduced transfer time when compared to industry standard polyacrylamide pre-cast gels.

The Scan

Study Finds Few FDA Post-Market Regulatory Actions Backed by Research, Public Assessments

A Yale University-led team examines in The BMJ safety signals from the US FDA Adverse Event Reporting System and whether they led to regulatory action.

Duke University Team Develops Programmable RNA Tool for Cell Editing

Researchers have developed an RNA-based editing tool that can target specific cells, as they describe in Nature.

Novel Gene Editing Approach for Treating Cystic Fibrosis

Researchers in Science Advances report on their development of a non-nuclease-based gene editing approach they hope to apply to treat cystic fibrosis.

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.