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Sigma-Aldrich, Caliper Life Sciences, Pharmaprojects, Thermo Electron

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Sigma-Aldrich and Caliper Life Sciences are collaborating to develop a variety of biochemical and reagent kits that can be applied to genomics, proteomics and drug discovery. One automated kit is the HIS-Select Integrated Lysis and Purification plates which provide a platform for purifying recombinant proteins. Validated automation protocols for these kits are now available for download at http://sigma-aldrich.com/automation.


Pharmaprojects, a database company, announced this week the launch of their drug target database called Pharmaprojects Version 5.1. The database contains over 1,300 protein drug targets for over 32,000 drug profiles tracked by Pharmaprojects since 1980. The database has 73 searchable fields for protein and chemical data.


Thermo Electron has introduced a new range of HPLC applications that can be used at ultra-high temperatures (up to 200 degrees Celcius) in reversed phase liquid chromatography. The HPLC applications use Hypercarb porous graphitic carbon columns, packed with three, five and seven micrometer particles.

Thermo’s new applications illustrate the use of temperature as a method development tool for the chromatographer.

The Scan

Fertility Fraud Found

Consumer genetic testing has uncovered cases of fertility fraud that are leading to lawsuits, according to USA Today.

Ties Between Vigorous Exercise, ALS in Genetically At-Risk People

Regular strenuous exercise could contribute to motor neuron disease development among those already at genetic risk, Sky News reports.

Test Warning

The Guardian writes that the US regulators have warned against using a rapid COVID-19 test that is a key part of mass testing in the UK.

Science Papers Examine Feedback Mechanism Affecting Xist, Continuous Health Monitoring for Precision Medicine

In Science this week: analysis of cis confinement of the X-inactive specific transcript, and more.