Skip to main content
Premium Trial:

Request an Annual Quote

Sigma-Aldrich, Bruker Daltonics, PerkinElmer, Caliper Life Sciences

Sigma-Aldrich last week launched its Proteomics Grade Trypsin Spin Column, which the company said will significantly reduce the time needed for the trypsin to digest samples.
The Trypsin Spin Column contains highly purified TPCK-treated porcine trypsin “immobilized on a chemically modified silica support to minimize non-specific absorption,” the company said. “This enables protein trypsination in one simple step; samples are ready for immediate analysis by mass spectrometry.”
The time needed for trypsin to digest complex protein samples will be reduced to 15 minutes from as much as 18 hours, Sigma-Aldrich said.

Bruker Daltonics this week launched its autoflex III Smartbeam vertical MALDI-TOF or TOF/TOF mass spectrometer, based on Bruker’s proprietary smartbeam laser technology. The instrument is particularly suited for MALDI molecular imaging applications in in vitro imaging of peptide and protein biomarker distributions in tissue sections, the company said.
The new autoflex is fully integrated into Bruker Daltonics’ solution packages such CliniProt, MALDI Molecular Imager, the Proteineer line, and the Proteineer LC line.
Bruker this week also launched the horizontal ultraflex III smartbeam MALDI-TOF/TOF mass spectrometer. The instrument has an improved smartbeam laser with computer-controlled settings of the laser focus size from 10 µm to 80 µm, the company said, allowing absorbing tissues to be scanned with a small laser focus and adjustable repetition rates from 1 Hz to 200 Hz.

PerkinElmer this week released the Clarus 600 series gas chromatograph and gas chromatograph/mass spectrometers.
The Clarus 600 GC is powered by a patent-pending oven design and delivers the fastest combined heat-up and cool-down rates for a conventional GC on the market, the company said. The new oven can cool from 450 degrees C to 50 degrees C in two minutes compared to up to six minutes for other GCs, PerkinElmer said.
The Clarus 600 GC/MS offers three different pumps now, and improvements include a compact footprint to maximize laboratory bench space, the company said.

Caliper Life Sciences this week unveiled its Xenogen IVIS Spectrum imaging system this week. The Xenogen system is the only in vivo optical imaging system that can perform high sensitivity bioluminescent imaging and advanced fluorescent imaging, the company said in a statement. Its dual illumination capability “enables tomographic localization of both shallow and deep tumors in 3D and reduces background interference,” Caliper said.
Caliper is taking orders for Xenogen which will be available in the first quarter of 2007.

The Scan

Study Links Genetic Risk for ADHD With Alzheimer's Disease

A higher polygenic risk score for attention-deficit/hyperactivity disorder is also linked to cognitive decline and Alzheimer's disease, a new study in Molecular Psychiatry finds.

Study Offers Insights Into Role of Structural Variants in Cancer

A new study in Nature using cell lines shows that structural variants can enable oncogene activation.

Computer Model Uses Genetics, Health Data to Predict Mental Disorders

A new model in JAMA Psychiatry finds combining genetic and health record data can predict a mental disorder diagnosis before one is made clinically.

Study Tracks Off-Target Gene Edits Linked to Epigenetic Features

Using machine learning, researchers characterize in BMC Genomics the potential off-target effects of 19 computed or experimentally determined epigenetic features during CRISPR-Cas9 editing.