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Roche Applied Science, SimBioSys, Bruker AXS


Roche Applied Science has released a new version of its Rapid Translation System (RTS) for cell-free protein expression. The RTS is a suite of E. coli lysate-based protein expression products and web-based services that can produce up to 150 mg of protein in a single o/n reaction. Roche Applied Science has also released RTS ProteoExpert, a new on-line program that suggests modified PCR primers for increasing the yield of protein.

SimBioSys of Toronto has released Sprout version 4.1, a tool for the rational design of drug-like biologically active molecules. The new version of the system provides a library to quickly generate peptides, in addition to the standard library for generating small molecule drug candidates. For further information visit

Bruker AXS has launched the X8 series of x-ray crystallography systems, the Madison, Wis.-based company said last week. The new line of instruments utilizes technology obtained through the acquisition of Nonius in April 2001, and includes the X8Proteum, Bruker's top-of-the-line instrument for high throughput structural proteomics. The X8 line also includes the X8Apex for determining the structure of small molecules, BruNo, a robotic system for sample changing of single crystals, and Linux and Windows software for data acquisition and structure analysis to accompany the Apex and Proteum instruments.


The Scan

Study Examines Insights Gained by Adjunct Trio RNA Sequencing in Complex Pediatric Disease Cases

Researchers in AJHG explore the diagnostic utility of adding parent-child RNA-seq to genome sequencing in dozens of families with complex, undiagnosed genetic disease.

Clinical Genomic Lab Survey Looks at Workforce Needs

Investigators use a survey approach in Genetics in Medicine Open to assess technologist applications, retention, and workforce gaps at molecular genetics and clinical cytogenetics labs in the US.

Study Considers Gene Regulatory Features Available by Sequence-Based Modeling

Investigators in Genome Biology set sequence-based models against observational and perturbation assay data, finding distal enhancer models lag behind promoter predictions.

Genetic Testing Approach Explores Origins of Blastocyst Aneuploidy

Investigators in AJHG distinguish between aneuploidy events related to meiotic missegregation in haploid cells and those involving post-zygotic mitotic errors and mosaicism.