US Patent 7,563,598. Detection of truncation mutations by mass spectrometery. Inventors: Alex Garvin, Sadanand Gite; Vladislav Bergo; Kenneth Rothschild. Assignee: Ambergen
Pertains to the detection and analysis of nascent proteins by mass spectrometry, in particular, truncated proteins translated within cellular or cell-free translations systems. "N-terminal and C-terminal epitopes introduced into these nascent proteins permit rapid and efficient isolation, as well as mass difference," according to the abstract.